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1150  structures 9091  species 0  interactions 144606  sequences 922  architectures

Clan: 6PGD_C (CL0106)


6-phosphogluconate dehydrogenase C-terminal-like superfamily Add an annotation

This helical domain is found associated with Rossmann domains.

This clan contains 14 families and the total number of domains in the clan is 144606. The clan was built by A Bateman.


This clan contains the following 14 member families:

3HCDH 6PGD ApbA_C DUF1932 DUF2520 HMD IlvC Mannitol_dh_C NAD_binding_11 NAD_Gly3P_dh_C Octopine_DH P5CR_dimer PDH_C UDPG_MGDP_dh

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
3HCDH (PF00725) 31477 (21.8%) View
NAD_binding_11 (PF14833) 20963 (14.5%) View
UDPG_MGDP_dh (PF00984) 18371 (12.7%) View
P5CR_dimer (PF14748) 12141 (8.4%) View
NAD_Gly3P_dh_C (PF07479) 12024 (8.3%) View
ApbA_C (PF08546) 10695 (7.4%) View
6PGD (PF00393) 9912 (6.9%) View
IlvC (PF01450) 9814 (6.8%) View
PDH_C (PF20463) 7404 (5.1%) View
Mannitol_dh_C (PF08125) 6400 (4.4%) View
DUF2520 (PF10728) 2950 (2.0%) View
DUF1932 (PF09130) 1398 (1.0%) View
Octopine_DH (PF02317) 1025 (0.7%) View
HMD (PF03201) 32 (0.0%) View
Total: 14 Total: 144606 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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