Summary
Six-hairpin glycosidase superfamily
This Clan includes CAZy clans GH-L, GH-M and GH-G. The members of this clan share a common structure composed of 6 helical hairpins. Most members of this superfamily are glycosyl hydrolase enzymes.
This clan contains 30 families and the total number of domains in the clan is 158051. The clan was built by A Bateman.
Members
This clan contains the following 30 member families:
Bac_rhamnosid6H C5-epim_C Cobalamin_bind DUF608 GDE_C GlcNAc_2-epim Glyco_hydro81C Glyco_hydro_100 Glyco_hydro_125 Glyco_hydro_127 Glyco_hydro_15 Glyco_hydro_36 Glyco_hydro_47 Glyco_hydro_48 Glyco_hydro_63 Glyco_hydro_65m Glyco_hydro_76 Glyco_hydro_8 Glyco_hydro_88 Glyco_hydro_9 Glycoamylase LANC_like Ldi Pec_lyase Prenyltrans SQHop_cyclase_C SQHop_cyclase_N TED_complement Terpene_synth TrehalaseExternal database links
CATH: | 1.50.10.30 |
SCOP: | 48208 |
Domain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
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Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Pfam family | Num. domains | Alignment |
---|---|---|
Prenyltrans (PF00432) | 28018 (17.7%) | View |
Glyco_hydro_47 (PF01532) | 12489 (7.9%) | View |
Glyco_hydro_15 (PF00723) | 11666 (7.4%) | View |
TED_complement (PF07678) | 8285 (5.2%) | View |
Glyco_hydro_9 (PF00759) | 8198 (5.2%) | View |
Bac_rhamnosid6H (PF17389) | 7508 (4.8%) | View |
Glyco_hydro_88 (PF07470) | 7062 (4.5%) | View |
Terpene_synth (PF01397) | 7034 (4.5%) | View |
SQHop_cyclase_C (PF13243) | 6041 (3.8%) | View |
Glyco_hydro_76 (PF03663) | 6026 (3.8%) | View |
Glyco_hydro_127 (PF07944) | 5660 (3.6%) | View |
Trehalase (PF01204) | 5331 (3.4%) | View |
SQHop_cyclase_N (PF13249) | 5299 (3.4%) | View |
LANC_like (PF05147) | 4966 (3.1%) | View |
Glyco_hydro_65m (PF03632) | 4888 (3.1%) | View |
GDE_C (PF06202) | 3612 (2.3%) | View |
continued |
Pfam family | Num. domains | Alignment |
---|---|---|
GlcNAc_2-epim (PF07221) | 3409 (2.2%) | View |
Glyco_hydro_63 (PF03200) | 3364 (2.1%) | View |
Glyco_hydro_36 (PF17167) | 2567 (1.6%) | View |
DUF608 (PF04685) | 2491 (1.6%) | View |
Glycoamylase (PF10091) | 2461 (1.6%) | View |
Glyco_hydro_125 (PF06824) | 2354 (1.5%) | View |
Glyco_hydro81C (PF17652) | 2345 (1.5%) | View |
Glyco_hydro_100 (PF12899) | 2307 (1.5%) | View |
Glyco_hydro_8 (PF01270) | 1568 (1.0%) | View |
C5-epim_C (PF06662) | 800 (0.5%) | View |
Cobalamin_bind (PF01122) | 788 (0.5%) | View |
Pec_lyase (PF09492) | 601 (0.4%) | View |
Glyco_hydro_48 (PF02011) | 552 (0.3%) | View |
Ldi (PF18566) | 361 (0.2%) | View |
Total: 30 | Total: 158051 | Clan alignment |
Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.
Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
Tree controls
HideThis tree shows the occurrence of the domains in this clan across different species. More...
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Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
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