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189  structures 7637  species 0  interactions 19114  sequences 225  architectures

Clan: Acylphosphatase (CL0622)


Acylphosphatase/BLUF domain-like superfamily Add an annotation

This superfamily has a ferredoxin fold. It contains the BLUF domain and the acylphosphatase family.

This clan contains 4 families and the total number of domains in the clan is 19114. The clan was built by A Bateman.

Literature references

  1. Anderson S, Dragnea V, Masuda S, Ybe J, Moffat K, Bauer C;, Biochemistry. 2005;44:7998-8005.: Structure of a novel photoreceptor, the BLUF domain of AppA from Rhodobacter sphaeroides. PUBMED:15924418 EPMC:15924418


This clan contains the following 4 member families:

Acylphosphatase BLUF DUF1115 UPF0176_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Acylphosphatase (PF00708) 8678 (45.4%) View
UPF0176_N (PF17773) 5219 (27.3%) View
DUF1115 (PF06544) 3012 (15.8%) View
BLUF (PF04940) 2205 (11.5%) View
Total: 4 Total: 19114 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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