Powering down the Pfam website
On October 5th, we began redirecting traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will remain available at pfam-legacy.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
146  structures 7604  species 0  interactions 437443  sequences 338  architectures

Clan: BPD_transp_1 (CL0404)


BPD transporter like Add an annotation

This clan contains families that are involved in transport of molecules across membranes. It includes the bacterial binding protein-dependent transport system inner membrane component, Pfam:PF00528, which is ATP dependent system involved in transport of a range of substrates [1-2].

This clan contains 4 families and the total number of domains in the clan is 437443. The clan was built by J Mistry and RD Finn.

Literature references

  1. Higgins CF, Hyde SC, Mimmack MM, Gileadi U, Gill DR, Gallagher MP; , J Bioenerg Biomembr 1990;22:571-592.: Binding protein-dependent transport systems. PUBMED:2229036 EPMC:2229036
  2. Ames GF;, Annu Rev Biochem. 1986;55:397-425.: Bacterial periplasmic transport systems: structure, mechanism, and evolution. PUBMED:3527048 EPMC:3527048


This clan contains the following 4 member families:

BPD_transp_1 DUF1430 FtsX LptF_LptG

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
BPD_transp_1 (PF00528) 345769 (79.0%) View
FtsX (PF02687) 82192 (18.8%) View
LptF_LptG (PF03739) 9358 (2.1%) View
DUF1430 (PF07242) 124 (0.0%) View
Total: 4 Total: 437443 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...