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501  structures 1516  species 0  interactions 48216  sequences 505  architectures

Clan: bZIP (CL0018)


bZIP-like leucine zipper Add an annotation

This family of eukaryotic transcription factors contain a basic region adjacent to a leucine zipper.

This clan contains 3 families and the total number of domains in the clan is 48216. The clan was built by DJ Studholme.

Literature references

  1. Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F; , Trends Plant Sci 2002;7:106-111.: bZIP transcription factors in Arabidopsis. PUBMED:11906833 EPMC:11906833
  2. Sinclair AJ; , J Gen Virol 2003;84:1941-1949.: bZIP proteins of human gammaherpesviruses. PUBMED:12867624 EPMC:12867624
  3. Hurst HC; , Protein Profile 1995;2:101-168.: Transcription factors 1: bZIP proteins. PUBMED:7780801 EPMC:7780801


This clan contains the following 3 member families:

bZIP_1 bZIP_2 bZIP_Maf

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
bZIP_1 (PF00170) 32564 (67.5%) View
bZIP_2 (PF07716) 10541 (21.9%) View
bZIP_Maf (PF03131) 5111 (10.6%) View
Total: 3 Total: 48216 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...