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346  structures 5707  species 0  interactions 12396  sequences 125  architectures

Clan: Rubredoxin (CL0045)


Rubredoxin-like Add an annotation

The Rubredoxin clan is comprised of three families:Rubredoxin, COX5B and desulforedoxin.Rubredoxin domains are small domains (5-6 kDa) and bind one iron atom tetrahedrally bound by four cysteine residues.Similar, desulforedoxin domains are small (4 kDa), but usually form homodimers. Each monomer binds one iron atom, but in a distorted tetrahedral arrangement. COX5B domains are membrane-anchored rubredoxin-like domains. The domain in the Rubredoxin clan are usually comprised of 2 alpha helixes and 2-3 beta strands.

This clan contains 5 families and the total number of domains in the clan is 12396. The clan was built by RD Finn.


This clan contains the following 5 member families:

COX5B Desulfoferrod_N Methyltransf_13 Rubredoxin zf-CHCC

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Rubredoxin (PF00301) 4993 (40.3%) View
zf-CHCC (PF10276) 3379 (27.3%) View
COX5B (PF01215) 1935 (15.6%) View
Methyltransf_13 (PF08421) 1323 (10.7%) View
Desulfoferrod_N (PF06397) 766 (6.2%) View
Total: 5 Total: 12396 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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