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1379  structures 5776  species 0  interactions 100341  sequences 3209  architectures

Clan: C_Lectin (CL0056)


C-type lectin-like superfamily Add an annotation

This clan contains domains that have a C-type lectin fold. Many of these are known or expected to mediate interactions with sugars.

This clan contains 13 families and the total number of domains in the clan is 100341. The clan was built by A Bateman.


This clan contains the following 13 member families:

APT C4 Chordopox_A33R DUF1554 DUF5075 Endostatin FGE-sulfatase Intimin_C InvE_AD Lectin_C Ly49 UL45 Xlink

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Lectin_C (PF00059) 65241 (65.0%) View
FGE-sulfatase (PF03781) 18023 (18.0%) View
Xlink (PF00193) 9478 (9.4%) View
C4 (PF01413) 5206 (5.2%) View
Endostatin (PF06482) 1640 (1.6%) View
Ly49 (PF08391) 308 (0.3%) View
UL45 (PF05473) 124 (0.1%) View
DUF5075 (PF16825) 117 (0.1%) View
DUF1554 (PF07588) 91 (0.1%) View
InvE_AD (PF05689) 66 (0.1%) View
Chordopox_A33R (PF05966) 29 (0.0%) View
APT (PF03440) 16 (0.0%) View
Intimin_C (PF07979) 2 (0.0%) View
Total: 13 Total: 100341 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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