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1157  structures 8739  species 0  interactions 38299  sequences 337  architectures

Clan: PELOTA (CL0101)


Pelota - RNA ribose binding superfamily Add an annotation

The members of this clan are all involved in binding to ribose sugar of RNA[1]. Indeed, the key RNA binding residues are conserved across the different families [1]. Members of this clan form mixed alpha-helical and beta-sheet structures [1][2].

This clan contains 7 families and the total number of domains in the clan is 38299. The clan was built by RD Finn.

Literature references

  1. Anantharaman V, Koonin EV, Aravind L;, Nucleic Acids Res. 2002;30:1427-1464.: Comparative genomics and evolution of proteins involved in RNA metabolism. PUBMED:11917006 EPMC:11917006
  2. Michel G, Sauve V, Larocque R, Li Y, Matte A, Cygler M; , Structure (Camb) 2002;10:1303-1315.: The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot. PUBMED:12377117 EPMC:12377117


This clan contains the following 7 member families:

eRF1_3 PELOTA_1 RbsD_FucU Ribosomal_L7Ae RNase_P_pop3 SpoU_sub_bind TSNR_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ribosomal_L7Ae (PF01248) 16683 (43.6%) View
SpoU_sub_bind (PF08032) 12483 (32.6%) View
eRF1_3 (PF03465) 4753 (12.4%) View
RbsD_FucU (PF05025) 3148 (8.2%) View
PELOTA_1 (PF15608) 763 (2.0%) View
RNase_P_pop3 (PF08228) 416 (1.1%) View
TSNR_N (PF04705) 53 (0.1%) View
Total: 7 Total: 38299 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...