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1554  structures 7884  species 0  interactions 42571  sequences 542  architectures

Clan: Calycin (CL0116)

Summary

Calycin superfamily Add an annotation

The calycin structural superfamily [1-3] includes the lipocalins, the fatty acid-binding proteins (FABPs).

This clan contains 44 families and the total number of domains in the clan is 42571. The clan was built by A Bateman.

Literature references

  1. Flower DR, North AC, Sansom CE; , Biochim Biophys Acta 2000;1482:9-24.: The lipocalin protein family: structural and sequence overview. PUBMED:11058743 EPMC:11058743
  2. Flower DR; , FEBS Lett 1993;333:99-102.: Structural relationship of streptavidin to the calycin protein superfamily. PUBMED:8224179 EPMC:8224179
  3. Flower DR, North AC, Attwood TK; , Protein Sci 1993;2:753-761.: Structure and sequence relationships in the lipocalins and related proteins. PUBMED:7684291 EPMC:7684291

Members

This clan contains the following 44 member families:

ApoM Calycin_like CpeS CpeT CrtC DUF1579 DUF1934 DUF2147 DUF3255 DUF3598 DUF3642 DUF3833 DUF4166 DUF4488 DUF4822 DUF4847 DUF4923 DUF5004 DUF5640 GH43_C His_binding Lipocalin Lipocalin_2 Lipocalin_3 Lipocalin_4 Lipocalin_5 Lipocalin_7 Lipocalin_8 Lipocalin_9 Luciferase_cat META MoaF MoaF_C MxiM Nitrophorin NlpE PA_decarbox Pallilysin Svf1 Svf1_C THAP4_heme-bd Triabin VDE ZinT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Lipocalin (PF00061) 9209 (21.6%) View
META (PF03724) 4572 (10.7%) View
Lipocalin_2 (PF08212) 3817 (9.0%) View
DUF2147 (PF09917) 3060 (7.2%) View
THAP4_heme-bd (PF08768) 2939 (6.9%) View
DUF1934 (PF09148) 1514 (3.6%) View
CrtC (PF07143) 1375 (3.2%) View
Lipocalin_9 (PF17186) 1345 (3.2%) View
Lipocalin_4 (PF13648) 1194 (2.8%) View
Lipocalin_7 (PF14651) 1115 (2.6%) View
DUF3833 (PF12915) 1033 (2.4%) View
Lipocalin_5 (PF13924) 989 (2.3%) View
NlpE (PF04170) 961 (2.3%) View
DUF4166 (PF13761) 908 (2.1%) View
Svf1_C (PF17187) 840 (2.0%) View
CpeT (PF06206) 829 (1.9%) View
Svf1 (PF08622) 820 (1.9%) View
DUF1579 (PF07617) 684 (1.6%) View
GH43_C (PF16369) 578 (1.4%) View
CpeS (PF09367) 573 (1.3%) View
VDE (PF07137) 553 (1.3%) View
PA_decarbox (PF05870) 527 (1.2%) View
ZinT (PF09223) 490 (1.2%) View
continued
Pfam family Num. domains Alignment
DUF3598 (PF12204) 446 (1.0%) View
ApoM (PF11032) 371 (0.9%) View
MoaF (PF10703) 273 (0.6%) View
MoaF_C (PF17409) 247 (0.6%) View
Calycin_like (PF13944) 188 (0.4%) View
DUF5004 (PF16395) 166 (0.4%) View
DUF4822 (PF16103) 154 (0.4%) View
DUF4923 (PF16270) 149 (0.4%) View
Lipocalin_3 (PF12702) 148 (0.3%) View
Lipocalin_8 (PF16585) 134 (0.3%) View
DUF4488 (PF14869) 78 (0.2%) View
Triabin (PF03973) 74 (0.2%) View
DUF5640 (PF18692) 60 (0.1%) View
DUF4847 (PF16139) 39 (0.1%) View
Nitrophorin (PF02087) 33 (0.1%) View
Pallilysin (PF18663) 31 (0.1%) View
His_binding (PF02098) 31 (0.1%) View
DUF3642 (PF12182) 21 (0.0%) View
MxiM (PF11441) 2 (0.0%) View
DUF3255 (PF11631) 1 (0.0%) View
Luciferase_cat (PF10285) 0 (0.0%) View
Total: 44 Total: 42571
No alignment ℹ
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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