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0  structures 6811  species 0  interactions 31474  sequences 166  architectures

Clan: DoxD-like (CL0131)


DoxD-like Add an annotation

The families in this clan are all membrane proteins. The DoxD family is found on enzymes involved in elemental sulphur oxidation [1]. The other families in this clan are poorly characterised.

This clan contains 11 families and the total number of domains in the clan is 31474. The clan was built by J Mistry.

Literature references

  1. Purschke WG, Schmidt CL, Petersen A, Schafer G; , J Bacteriol 1997;179:1344-1353.: The terminal quinol oxidase of the hyperthermophilic archaeon Acidianus ambivalens exhibits a novel subunit structure and gene organization. PUBMED:9023221 EPMC:9023221


This clan contains the following 11 member families:

DoxD DoxX DoxX_2 DoxX_3 DUF417 HR_lesion LMF1 MauE SURF2 SURF4 TMEM101

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DoxX (PF07681) 15656 (49.7%) View
DoxX_2 (PF13564) 5646 (17.9%) View
LMF1 (PF06762) 3187 (10.1%) View
SURF4 (PF02077) 1810 (5.8%) View
MauE (PF07291) 1625 (5.2%) View
DoxX_3 (PF13781) 786 (2.5%) View
HR_lesion (PF05514) 735 (2.3%) View
DUF417 (PF04224) 722 (2.3%) View
SURF2 (PF05477) 710 (2.3%) View
TMEM101 (PF15111) 309 (1.0%) View
DoxD (PF04173) 288 (0.9%) View
Total: 11 Total: 31474 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...