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323  structures 3088  species 0  interactions 15425  sequences 299  architectures

Clan: DNA_pol_B-like (CL0194)


DNA polymerase B like Add an annotation

DNA polymerases replicate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of a growing chain of DNA. They use a complementary DNA chain as a template.`

This clan contains 5 families and the total number of domains in the clan is 15425. The clan was built by J Mistry.

Literature references

  1. Zhou M, Mao C, Rodriguez AC, Kiefer JR, Kucera RB, Beese LS; , Acta Crystallogr D Biol Crystallogr 1998;54:994-995.: Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. PUBMED:9757117 EPMC:9757117


This clan contains the following 5 member families:

divDNApol DNA_pol_B DNA_pol_B_2 DUF1744 Pox_F12L

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DNA_pol_B (PF00136) 10804 (70.0%) View
DNA_pol_B_2 (PF03175) 2558 (16.6%) View
DUF1744 (PF08490) 1971 (12.8%) View
divDNApol (PF20286) 55 (0.4%) View
Pox_F12L (PF03337) 37 (0.2%) View
Total: 5 Total: 15425 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...