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323  structures 3088  species 0  interactions 15425  sequences 299  architectures

Clan: DNA_pol_B-like (CL0194)

Summary

DNA polymerase B like Add an annotation

DNA polymerases replicate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of a growing chain of DNA. They use a complementary DNA chain as a template.`

This clan contains 5 families and the total number of domains in the clan is 15425. The clan was built by J Mistry.

Literature references

  1. Zhou M, Mao C, Rodriguez AC, Kiefer JR, Kucera RB, Beese LS; , Acta Crystallogr D Biol Crystallogr 1998;54:994-995.: Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. PUBMED:9757117 EPMC:9757117

Members

This clan contains the following 5 member families:

divDNApol DNA_pol_B DNA_pol_B_2 DUF1744 Pox_F12L

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DNA_pol_B (PF00136) 10804 (70.0%) View
DNA_pol_B_2 (PF03175) 2558 (16.6%) View
DUF1744 (PF08490) 1971 (12.8%) View
divDNApol (PF20286) 55 (0.4%) View
Pox_F12L (PF03337) 37 (0.2%) View
Total: 5 Total: 15425 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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