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522  structures 1203  species 0  interactions 6125  sequences 402  architectures

Clan: Adhesin (CL0204)

Summary

Bacterial adhesin superfamily Add an annotation

This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.

This clan contains 17 families and the total number of domains in the clan is 6125. The clan was built by A Bateman.

Literature references

  1. Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017

Members

This clan contains the following 17 member families:

Adhesin_Dr AfaD AgI_II_C2 Antig_Caf1 Antigen_C Collagen_bind DUF1120 Fim-adh_lectin FimA Fimbrial FimH_man-bind GramPos_pilinBB PapG_N Saf-Nte_pilin SCPU SdrG_C_C Sgo0707_N2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Fimbrial (PF00419) 2209 (36.1%) View
SCPU (PF05229) 1617 (26.4%) View
Collagen_bind (PF05737) 1104 (18.0%) View
GramPos_pilinBB (PF16569) 397 (6.5%) View
FimA (PF16970) 243 (4.0%) View
AgI_II_C2 (PF17998) 173 (2.8%) View
DUF1120 (PF06551) 128 (2.1%) View
Antigen_C (PF16364) 90 (1.5%) View
Sgo0707_N2 (PF20623) 52 (0.8%) View
SdrG_C_C (PF10425) 52 (0.8%) View
FimH_man-bind (PF09160) 51 (0.8%) View
AfaD (PF05775) 6 (0.1%) View
Saf-Nte_pilin (PF09460) 2 (0.0%) View
Antig_Caf1 (PF09255) 1 (0.0%) View
Fim-adh_lectin (PF09222) 0 (0.0%) View
PapG_N (PF03627) 0 (0.0%) View
Adhesin_Dr (PF04619) 0 (0.0%) View
Total: 17 Total: 6125 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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