Summary
Bacterial adhesin superfamily
This superfamily includes a variety of bacterial adhesins that have a jelly-roll beta-barrel fold [1]. These domains are involved in sugar recognition.
This clan contains 17 families and the total number of domains in the clan is 6125. The clan was built by A Bateman.
Literature references
- Merckel MC, Tanskanen J, Edelman S, Westerlund-Wikstrom B, Korhonen TK, Goldman A; , J Mol Biol 2003;331:897-905.: The structural basis of receptor-binding by Escherichia coli associated with diarrhea and septicemia. PUBMED:12909017 EPMC:12909017
Members
This clan contains the following 17 member families:
Adhesin_Dr AfaD AgI_II_C2 Antig_Caf1 Antigen_C Collagen_bind DUF1120 Fim-adh_lectin FimA Fimbrial FimH_man-bind GramPos_pilinBB PapG_N Saf-Nte_pilin SCPU SdrG_C_C Sgo0707_N2External database links
CATH: | 2.60.40.1090 |
SCOP: | 49401 |
Domain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
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Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Pfam family | Num. domains | Alignment |
---|---|---|
Fimbrial (PF00419) | 2209 (36.1%) | View |
SCPU (PF05229) | 1617 (26.4%) | View |
Collagen_bind (PF05737) | 1104 (18.0%) | View |
GramPos_pilinBB (PF16569) | 397 (6.5%) | View |
FimA (PF16970) | 243 (4.0%) | View |
AgI_II_C2 (PF17998) | 173 (2.8%) | View |
DUF1120 (PF06551) | 128 (2.1%) | View |
Antigen_C (PF16364) | 90 (1.5%) | View |
Sgo0707_N2 (PF20623) | 52 (0.8%) | View |
SdrG_C_C (PF10425) | 52 (0.8%) | View |
FimH_man-bind (PF09160) | 51 (0.8%) | View |
AfaD (PF05775) | 6 (0.1%) | View |
Saf-Nte_pilin (PF09460) | 2 (0.0%) | View |
Antig_Caf1 (PF09255) | 1 (0.0%) | View |
Fim-adh_lectin (PF09222) | 0 (0.0%) | View |
PapG_N (PF03627) | 0 (0.0%) | View |
Adhesin_Dr (PF04619) | 0 (0.0%) | View |
Total: 17 | Total: 6125 | Clan alignment |
Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.
Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
Tree controls
HideThis tree shows the occurrence of the domains in this clan across different species. More...
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Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
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