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12  structures 6435  species 0  interactions 11060  sequences 33  architectures

Clan: FtsL (CL0225)


FtsL-like superfamily Add an annotation

This clan includes two proteins that are known to interact, FtsL and DivIC which are part of a trimeric complex with DivIB [2]. DivIC and FtsL are bacterial proteins essential for cell division.

This clan contains 4 families and the total number of domains in the clan is 11060. The clan was built by A Bateman.

Literature references

  1. Sievers J, Errington J; , Mol Microbiol 2000;36:846-855.: The Bacillus subtilis cell division protein FtsL localizes to sites of septation and interacts with DivIC. PUBMED:10844672 EPMC:10844672
  2. Noirclerc-Savoye M, Le Gouellec A, Morlot C, Dideberg O, Vernet T, Zapun A; , Mol Microbiol. 2005;55:413-424.: In vitro reconstitution of a trimeric complex of DivIB, DivIC and FtsL, and their transient co-localization at the division site in Streptococcus pneumoniae. PUBMED:15659160 EPMC:15659160


This clan contains the following 4 member families:

DivIC FtsL FtsL_2 ZapB

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DivIC (PF04977) 7815 (70.7%) View
FtsL (PF04999) 1804 (16.3%) View
FtsL_2 (PF19579) 881 (8.0%) View
ZapB (PF06005) 560 (5.1%) View
Total: 4 Total: 11060 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...