Powering down the Pfam website
On October 5th, we began redirecting traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will remain available at pfam-legacy.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
653  structures 8620  species 0  interactions 146660  sequences 5054  architectures

Clan: Pec_lyase-like (CL0268)


Pectate lyase-like beta helix Add an annotation

This superfamily all contain a right handed beta helix similar to that first found in pectate lyase [1].

This clan contains 41 families and the total number of domains in the clan is 146660. The clan was built by A Bateman.

Literature references

  1. Jenkins J, Mayans O, Pickersgill R; , J Struct Biol. 1998;122:236-246.: Structure and evolution of parallel beta-helix proteins. PUBMED:9724625 EPMC:9724625


This clan contains the following 41 member families:

AC_1 Adeno_E1B_55K AIDA B_solenoid_dext B_solenoid_ydck Bactofilin Beta_helix Beta_helix_2 Beta_helix_3 Chlam_PMP Chondroitinas_B Cthe_2159 Disaggr_assoc DUF1565 DUF2154 DUF2807 DUF3737 DUF4097 DUF4957 DUF5649 End_N_terminal FapA Fil_haemagg Fil_haemagg_2 Glyco_hydro_28 Glyco_hydro_49 Glyco_hydro_92 IPU_b_solenoid MinC_C NosD PATR Pectate_lyase Pectate_lyase_3 Pectate_lyase_4 Pectinesterase Pertactin Phage_spike_2 PhageP22-tail Toast_rack_N TPS VacA

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Beta_helix (PF13229) 23649 (16.1%) View
Glyco_hydro_28 (PF00295) 19612 (13.4%) View
Pectinesterase (PF01095) 15781 (10.8%) View
PATR (PF12951) 11201 (7.6%) View
Pectate_lyase_3 (PF12708) 9470 (6.5%) View
Pectate_lyase_4 (PF00544) 8032 (5.5%) View
Glyco_hydro_92 (PF07971) 7669 (5.2%) View
DUF4097 (PF13349) 6983 (4.8%) View
Fil_haemagg (PF05594) 5463 (3.7%) View
DUF2807 (PF10988) 4980 (3.4%) View
Bactofilin (PF04519) 4804 (3.3%) View
Fil_haemagg_2 (PF13332) 3645 (2.5%) View
TPS (PF05860) 3432 (2.3%) View
NosD (PF05048) 3384 (2.3%) View
MinC_C (PF03775) 3201 (2.2%) View
DUF2154 (PF09922) 2701 (1.8%) View
Pectate_lyase (PF03211) 2184 (1.5%) View
FapA (PF03961) 1622 (1.1%) View
Cthe_2159 (PF14262) 1502 (1.0%) View
DUF1565 (PF07602) 991 (0.7%) View
Chondroitinas_B (PF14592) 921 (0.6%) View
Pfam family Num. domains Alignment
DUF5649 (PF18886) 861 (0.6%) View
AC_1 (PF18883) 822 (0.6%) View
Chlam_PMP (PF02415) 712 (0.5%) View
Beta_helix_3 (PF18889) 706 (0.5%) View
DUF3737 (PF12541) 452 (0.3%) View
B_solenoid_ydck (PF18836) 374 (0.3%) View
Pertactin (PF03212) 331 (0.2%) View
AIDA (PF16168) 274 (0.2%) View
DUF4957 (PF16318) 243 (0.2%) View
IPU_b_solenoid (PF18783) 115 (0.1%) View
Glyco_hydro_49 (PF03718) 115 (0.1%) View
B_solenoid_dext (PF18841) 110 (0.1%) View
PhageP22-tail (PF09251) 81 (0.1%) View
Toast_rack_N (PF17115) 73 (0.0%) View
Adeno_E1B_55K (PF01696) 54 (0.0%) View
Beta_helix_2 (PF18835) 41 (0.0%) View
Disaggr_assoc (PF08480) 37 (0.0%) View
End_N_terminal (PF12218) 26 (0.0%) View
VacA (PF02691) 4 (0.0%) View
Phage_spike_2 (PF18781) 2 (0.0%) View
Total: 41 Total: 146660
No alignment ℹ

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...