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2  structures 61  species 0  interactions 451  sequences 14  architectures

Clan: Allatostatin (CL0284)


Allatostatin superfamily Add an annotation

Allatostatins are pleiotropic neuropeptides. In some insects they are known to inhibit the synthesis of juvenile hormone, an important regulator of development and reproduction. The full role of allatostatins in hormone production is still unclear [1].

This clan contains 2 families and the total number of domains in the clan is 451. The clan was built by J Mistry.

Literature references

  1. Stay B, Tobe SS; , Annu Rev Entomol. 2007;52:277-299.: The role of allatostatins in juvenile hormone synthesis in insects and crustaceans. PUBMED:16968202 EPMC:16968202


This clan contains the following 2 member families:

Allatostatin Carcinustatin

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Allatostatin (PF05953) 442 (98.0%) View
Carcinustatin (PF08261) 9 (2.0%) View
Total: 2 Total: 451 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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