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12  structures 2518  species 0  interactions 5012  sequences 20  architectures

Clan: DMSO_reductase (CL0308)


Dimethyl sulfoxide reductase type II family Add an annotation

This clan includes members that are type II dimethyl sulfoxide reductase families, all of which are also membrane anchor proteins belonging to the iron-sulfur molybdoenzyme (CISM) family [1].

This clan contains 3 families and the total number of domains in the clan is 5012. The clan was built by P Coggill.

Literature references

  1. Rothery RA, Workun GJ, Weiner JH; , Biochim Biophys Acta. 2008;1778:1897-1929.: The prokaryotic complex iron-sulfur molybdoenzyme family. PUBMED:17964535 EPMC:17964535


This clan contains the following 3 member families:

DmsC NrfD NrfD_2

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
NrfD (PF03916) 3748 (74.8%) View
DmsC (PF04976) 1256 (25.1%) View
NrfD_2 (PF14589) 8 (0.2%) View
Total: 3 Total: 5012 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...