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403  structures 7692  species 0  interactions 19076  sequences 226  architectures

Clan: RMMBL_DRMBL (CL0398)


RNA/DNA-metabolising metallo-beta-lactamase motif Add an annotation

This clan contains the fifth motif found in RNA and DNA metabolising metallo-beta-lactamases. The fifth motif appears to be specific to function [1].

This clan contains 2 families and the total number of domains in the clan is 19076. The clan was built by J Mistry.

Literature references

  1. Callebaut I, Moshous D, Mornon JP, de Villartay JP; , Nucleic Acids Res 2002;30:3592-3601.: Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family. PUBMED:12177301 EPMC:12177301


This clan contains the following 2 member families:


Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
RMMBL (PF07521) 15389 (80.7%) View
DRMBL (PF07522) 3687 (19.3%) View
Total: 2 Total: 19076 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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