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1305  structures 8817  species 0  interactions 247322  sequences 3396  architectures

Clan: PDZ-like (CL0466)


PDZ domain-like peptide-binding superfamily Add an annotation

This superfamily comprises families of PDZ domains, which are peptide binding sites.

This clan contains 11 families and the total number of domains in the clan is 247322. The clan was built by P Coggill.


This clan contains the following 11 member families:

DUF6288 EBP50_C GRASP55_65 PDZ PDZ_1 PDZ_2 PDZ_3 PDZ_4 PDZ_5 PDZ_6 Tricorn_PDZ

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PDZ (PF00595) 167674 (67.8%) View
PDZ_6 (PF17820) 36027 (14.6%) View
PDZ_2 (PF13180) 32069 (13.0%) View
GRASP55_65 (PF04495) 3339 (1.4%) View
PDZ_1 (PF12812) 2248 (0.9%) View
PDZ_5 (PF17817) 1864 (0.8%) View
Tricorn_PDZ (PF14685) 1468 (0.6%) View
PDZ_3 (PF17815) 1447 (0.6%) View
EBP50_C (PF09007) 1064 (0.4%) View
DUF6288 (PF19805) 96 (0.0%) View
PDZ_4 (PF17816) 26 (0.0%) View
Total: 11 Total: 247322 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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