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50  structures 921  species 0  interactions 7073  sequences 139  architectures

Clan: PHM_PNGase_F (CL0612)


PHM/PNGase F superfamily Add an annotation

Members of this superfamily adopt a beta-sandwich fold. With two adjacent domains in a protein interacting in the same way as nucleoplasmins that share the same fold. This superfamily includes the Peptide-N-glycosidase F enzymes and the peptidylglycine alpha-hydroxylating monooxygenase enzymes.

This clan contains 4 families and the total number of domains in the clan is 7073. The clan was built by A Bateman.


This clan contains the following 4 member families:

Cu2_monoox_C Cu2_monooxygen N-glycanase_C N-glycanase_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Cu2_monoox_C (PF03712) 3275 (46.3%) View
Cu2_monooxygen (PF01082) 2870 (40.6%) View
N-glycanase_C (PF09113) 527 (7.5%) View
N-glycanase_N (PF09112) 401 (5.7%) View
Total: 4 Total: 7073 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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