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165  structures 1590  species 0  interactions 9140  sequences 126  architectures

Clan: Mad2 (CL0651)


Mad2 superfamily Add an annotation

This clan contains 5 families and the total number of domains in the clan is 9140. The clan was built by A Bateman.


This clan contains the following 5 member families:

ATG101 ATG13 bacHORMA_2 HORMA p31comet

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
HORMA (PF02301) 4712 (51.6%) View
ATG13 (PF10033) 2340 (25.6%) View
ATG101 (PF07855) 1610 (17.6%) View
p31comet (PF06581) 425 (4.6%) View
bacHORMA_2 (PF18173) 53 (0.6%) View
Total: 5 Total: 9140 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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