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49  structures 404  species 0  interactions 442  sequences 55  architectures

Clan: Vmethyltransf (CL0696)


Viral methyltranferase superfamily Add an annotation

This entry includes several related families of viral methyltransferase enzymes that are involed in mRNA capping [1].

This clan contains 3 families and the total number of domains in the clan is 442. The clan was built by A Bateman.

Literature references

  1. Ahola T, Karlin DG;, Biol Direct. 2015;10:16.: Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses. PUBMED:25886938 EPMC:25886938


This clan contains the following 3 member families:

Chropara_Vmeth Noda_Vmethyltr Vmethyltransf

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Vmethyltransf (PF01660) 399 (90.3%) View
Noda_Vmethyltr (PF19222) 26 (5.9%) View
Chropara_Vmeth (PF19223) 17 (3.8%) View
Total: 3 Total: 442 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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