Summary
NADH dehydrogenase I, subunit N
This superfamily contains proteins from the families Oxidored_q1 and NADHdeh_related. The Oxidored_q1 family is part of complex I which catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane. Many members of the NADHdeh_related family are archaeal and bacterial, indicating the evolutionary origins of ComplexI.
This clan contains 3 families and the total number of domains in the clan is 45618. The clan was built by A Bateman.
Members
This clan contains the following 3 member families:
NADHdeh_related NADHdh Proton_antipo_MDomain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
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Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Pfam family | Num. domains | Alignment |
---|---|---|
Proton_antipo_M (PF00361) | 36719 (80.5%) | View |
NADHdh (PF00146) | 8869 (19.4%) | View |
NADHdeh_related (PF10125) | 30 (0.1%) | View |
Total: 3 | Total: 45618 | Clan alignment |
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Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
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Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
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