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1173  structures 6878  species 0  interactions 81944  sequences 1002  architectures

Clan: Cytochrome-c (CL0318)


Cytochrome c superfamily Add an annotation

This family includes proteins where a covalently-bound haem completes the core. The core is three helices in an open folded leaf formation. The members are monodomain cytochromes.

This clan contains 13 families and the total number of domains in the clan is 81944. The clan was built by P Coggill.


This clan contains the following 13 member families:

CCP_MauG Cytochrom_C Cytochrom_C1 Cytochrom_C550 Cytochrome-c551 Cytochrome_CBB3 Dehyd-heme_bind DHC DHOR DUF1924 FixO Haem_bd PSCyt1

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Cytochrome_CBB3 (PF13442) 30218 (36.9%) View
Cytochrom_C (PF00034) 29176 (35.6%) View
CCP_MauG (PF03150) 5277 (6.4%) View
PSCyt1 (PF07635) 4952 (6.0%) View
Cytochrom_C1 (PF02167) 4684 (5.7%) View
FixO (PF02433) 3282 (4.0%) View
DHOR (PF06537) 2268 (2.8%) View
Haem_bd (PF14376) 920 (1.1%) View
DHC (PF09626) 486 (0.6%) View
DUF1924 (PF09086) 260 (0.3%) View
Cytochrom_C550 (PF14495) 227 (0.3%) View
Dehyd-heme_bind (PF09098) 175 (0.2%) View
Cytochrome-c551 (PF10643) 19 (0.0%) View
Total: 13 Total: 81944 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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