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928  structures 8851  species 0  interactions 32612  sequences 156  architectures

Clan: DHFred (CL0387)

Summary

Dihydrofolate reductase-like Add an annotation

Superfamily contains the dihydrofolate reductases and the RibD C-terminal domain-like including HTP reductase families.

This clan contains 2 families and the total number of domains in the clan is 32612. The clan was built by P Coggill.

Members

This clan contains the following 2 member families:

DHFR_1 RibD_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
RibD_C (PF01872) 23680 (72.6%) View
DHFR_1 (PF00186) 8932 (27.4%) View
Total: 2 Total: 32612 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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