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23  structures 2179  species 0  interactions 4833  sequences 193  architectures

Clan: G5 (CL0593)


B region of SasG biofilm-forming surface protein Add an annotation

This superfamily is characterised by repeating domains, G5 and SasG-E, where the SasG-E domain is a truncated form of the G5 domain. Member domains are composed of triple-stranded single-layer beta-sheets connected by an intertwined motif, which leads to a strand switch [1]. These domain-members occur on extracellular proteins which, in Staphylococcus spp, form biofilms.

This clan contains 2 families and the total number of domains in the clan is 4833. The clan was built by A Bateman and P Coggill.

Literature references

  1. Gruszka DT, Wojdyla JA, Bingham RJ, Turkenburg JP, Manfield IW, Steward A, Leech AP, Geoghegan JA, Foster TJ, Clarke J, Potts JR;, Proc Natl Acad Sci U S A. 2012;109:E1011-E1018.: Staphylococcal biofilm-forming protein has a contiguous rod-like structure. PUBMED:22493247 EPMC:22493247


This clan contains the following 2 member families:

G5 SasG_E

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
G5 (PF07501) 4813 (99.6%) View
SasG_E (PF17041) 20 (0.4%) View
Total: 2 Total: 4833 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...