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237  structures 8484  species 0  interactions 58145  sequences 866  architectures

Clan: GH_CE (CL0158)


Glycoside hydrolase/deacetylase superfamily Add an annotation

This superfamily contains diverse enzymes that act on carbohydrates including both hydrolases and deacetylases.

This clan contains 11 families and the total number of domains in the clan is 58145. The clan was built by A Bateman.


This clan contains the following 11 member families:

DUF2194 DUF2334 DUF3863 Glyco_hydro_38N Glyco_hydro_57 GxGYxYP_C LamB_YcsF Polysacc_deac_1 Polysacc_deac_2 Polysacc_deac_3 YdjC

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Polysacc_deac_1 (PF01522) 35250 (60.6%) View
Glyco_hydro_38N (PF01074) 9723 (16.7%) View
LamB_YcsF (PF03746) 4879 (8.4%) View
Glyco_hydro_57 (PF03065) 2492 (4.3%) View
YdjC (PF04794) 2256 (3.9%) View
Polysacc_deac_2 (PF04748) 1935 (3.3%) View
DUF2334 (PF10096) 948 (1.6%) View
GxGYxYP_C (PF14323) 371 (0.6%) View
DUF2194 (PF09960) 233 (0.4%) View
DUF3863 (PF12979) 40 (0.1%) View
Polysacc_deac_3 (PF15421) 18 (0.0%) View
Total: 11 Total: 58145 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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