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1336  structures 9143  species 0  interactions 413736  sequences 5270  architectures

Clan: GT-B (CL0113)


Glycosyl transferase clan GT-B Add an annotation

This is the GT-B clan that contains diverse glycosyltransferases that possess a Rossmann like fold [1].

This clan contains 51 families and the total number of domains in the clan is 413736. The clan was built by A Bateman.

Literature references

  1. Liu J, Mushegian A; , Protein Sci 2003;12:1418-1431.: Three monophyletic superfamilies account for the majority of the known glycosyltransferases. PUBMED:12824488 EPMC:12824488


This clan contains the following 51 member families:

A-2_8-polyST AGT ALG11_N Alg14 Asp1 Capsule_synth DUF1205 DUF1972 DUF2827 DUF3492 DUF354 DUF6716 Epimerase_2 FucT_N FUT8_N_cat Glyco_tran_28_C Glyco_trans_1_2 Glyco_trans_1_3 Glyco_trans_1_4 Glyco_trans_4_2 Glyco_trans_4_3 Glyco_trans_4_4 Glyco_trans_4_5 Glyco_transf_10 Glyco_transf_11 Glyco_transf_20 Glyco_transf_28 Glyco_transf_4 Glyco_transf_41 Glyco_transf_5 Glyco_transf_52 Glyco_transf_56 Glyco_transf_9 Glyco_transf_90 Glycogen_syn Glycos_transf_1 Glycos_transf_N Glyphos_transf LpxB MGDG_synth Mito_fiss_Elm1 NodZ O-FucT Phosphorylase PIGA PM0188 PS_pyruv_trans Sua5_C Sucrose_synth T4-Gluco-transf UDPGT

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Glycos_transf_1 (PF00534) 99339 (24.0%) View
Glyco_transf_4 (PF13439) 57840 (14.0%) View
UDPGT (PF00201) 47187 (11.4%) View
Glyco_trans_1_4 (PF13692) 25855 (6.2%) View
Glyco_tran_28_C (PF04101) 15495 (3.7%) View
Glyco_transf_28 (PF03033) 13553 (3.3%) View
O-FucT (PF10250) 11958 (2.9%) View
Phosphorylase (PF00343) 11375 (2.7%) View
Glyco_trans_4_4 (PF13579) 10312 (2.5%) View
Glyco_transf_20 (PF00982) 10243 (2.5%) View
Glyco_transf_9 (PF01075) 10216 (2.5%) View
Glyco_transf_5 (PF08323) 8626 (2.1%) View
Glyco_transf_41 (PF13844) 8170 (2.0%) View
Epimerase_2 (PF02350) 8028 (1.9%) View
Glyco_transf_90 (PF05686) 6898 (1.7%) View
PS_pyruv_trans (PF04230) 6254 (1.5%) View
Glyco_transf_10 (PF00852) 5808 (1.4%) View
Sua5_C (PF03481) 4997 (1.2%) View
Glyphos_transf (PF04464) 4990 (1.2%) View
LpxB (PF02684) 4721 (1.1%) View
Glycos_transf_N (PF04413) 4669 (1.1%) View
Glyco_trans_1_2 (PF13524) 4271 (1.0%) View
Capsule_synth (PF05159) 3689 (0.9%) View
Sucrose_synth (PF00862) 3043 (0.7%) View
Glycogen_syn (PF05693) 3030 (0.7%) View
MGDG_synth (PF06925) 2655 (0.6%) View
Pfam family Num. domains Alignment
Alg14 (PF08660) 2403 (0.6%) View
Glyco_trans_4_2 (PF13477) 2369 (0.6%) View
Glyco_transf_11 (PF01531) 1925 (0.5%) View
PIGA (PF08288) 1841 (0.4%) View
ALG11_N (PF15924) 1828 (0.4%) View
Mito_fiss_Elm1 (PF06258) 1409 (0.3%) View
FUT8_N_cat (PF19745) 1189 (0.3%) View
DUF3492 (PF11997) 1113 (0.3%) View
Glyco_trans_1_3 (PF13528) 1014 (0.2%) View
DUF1205 (PF06722) 909 (0.2%) View
Glyco_trans_4_3 (PF12000) 784 (0.2%) View
A-2_8-polyST (PF07388) 641 (0.2%) View
Glyco_trans_4_5 (PF16994) 627 (0.2%) View
DUF1972 (PF09314) 610 (0.1%) View
DUF6716 (PF20471) 526 (0.1%) View
DUF354 (PF04007) 399 (0.1%) View
Glyco_transf_56 (PF07429) 278 (0.1%) View
DUF2827 (PF10933) 169 (0.0%) View
Glyco_transf_52 (PF07922) 137 (0.0%) View
Asp1 (PF16993) 137 (0.0%) View
FucT_N (PF18025) 125 (0.0%) View
NodZ (PF05830) 42 (0.0%) View
PM0188 (PF11477) 19 (0.0%) View
AGT (PF11440) 11 (0.0%) View
T4-Gluco-transf (PF09198) 9 (0.0%) View
Total: 51 Total: 413736
No alignment ℹ

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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