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1218  structures 8991  species 0  interactions 123466  sequences 947  architectures

Clan: GroES (CL0296)


GroES-like superfamily Add an annotation

This superfamily includes the GroES protein as well as the N-terminal GroES-like domain from Alcohol dehydrogenase.

This clan contains 3 families and the total number of domains in the clan is 123466. The clan was built by A Bateman.

Literature references

  1. Taneja B, Mande SC; , Protein Eng 1999;12:815-818.: Conserved structural features and sequence patterns in the GroES fold family. PUBMED:10556240 EPMC:10556240
  2. Murzin AG; , Curr Opin Struct Biol 1996;6:386-394.: Structural classification of proteins: new superfamilies. PUBMED:8804825 EPMC:8804825


This clan contains the following 3 member families:

ADH_N ADH_N_2 Cpn10

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
ADH_N (PF08240) 100412 (81.3%) View
Cpn10 (PF00166) 13521 (11.0%) View
ADH_N_2 (PF16884) 9533 (7.7%) View
Total: 3 Total: 123466 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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