Summary
LysE transporter superfamily
This clan includes a diverse range of transporter families [1].
This clan contains 19 families and the total number of domains in the clan is 133318. The clan was built by A Bateman.
Literature references
- Vrljic M, Garg J, Bellmann A, Wachi S, Freudl R, Malecki MJ, Sahm H, Kozina VJ, Eggeling L, Saier MH Jr, Eggeling L, Saier MH Jr; , J Mol Microbiol Biotechnol. 1999;1:327-336.: The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. PUBMED:10943564 EPMC:10943564
Members
This clan contains the following 19 member families:
BacA Cad Colicin_V DsbD DsbD_2 DUF475 DUF6044 FTR1 HupE_UreJ HupE_UreJ_2 LysE MarC Mntp NicO OFeT_1 SfLAP TauE TerC UPF0016Domain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
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Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Pfam family | Num. domains | Alignment |
---|---|---|
TauE (PF01925) | 32027 (24.0%) | View |
LysE (PF01810) | 23774 (17.8%) | View |
TerC (PF03741) | 11049 (8.3%) | View |
DsbD (PF02683) | 10963 (8.2%) | View |
UPF0016 (PF01169) | 10303 (7.7%) | View |
BacA (PF02673) | 8870 (6.7%) | View |
Colicin_V (PF02674) | 6920 (5.2%) | View |
MarC (PF01914) | 6140 (4.6%) | View |
FTR1 (PF03239) | 4701 (3.5%) | View |
Mntp (PF02659) | 3906 (2.9%) | View |
NicO (PF03824) | 3631 (2.7%) | View |
DsbD_2 (PF13386) | 3436 (2.6%) | View |
HupE_UreJ_2 (PF13795) | 2451 (1.8%) | View |
HupE_UreJ (PF04955) | 1386 (1.0%) | View |
SfLAP (PF11139) | 1237 (0.9%) | View |
DUF475 (PF04332) | 1175 (0.9%) | View |
Cad (PF03596) | 1012 (0.8%) | View |
DUF6044 (PF19510) | 253 (0.2%) | View |
OFeT_1 (PF16955) | 84 (0.1%) | View |
Total: 19 | Total: 133318 | Clan alignment |
Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.
Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
Tree controls
HideThis tree shows the occurrence of the domains in this clan across different species. More...
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Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
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