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14  structures 4510  species 0  interactions 7102  sequences 53  architectures

Clan: MurF-HprK_N (CL0365)


MurF and HprK N-domain-like superfamily Add an annotation

This includes both the MurE/MurF-ligases N-terminal domain and HPr kinase/phosphatase HprK N-terminal domain superfamilies.

This clan contains 2 families and the total number of domains in the clan is 7102. The clan was built by A Bateman.


This clan contains the following 2 member families:

DRTGG Hpr_kinase_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DRTGG (PF07085) 4484 (63.1%) View
Hpr_kinase_N (PF02603) 2618 (36.9%) View
Total: 2 Total: 7102 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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