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44  structures 8888  species 0  interactions 127313  sequences 453  architectures

Clan: MviN_MATE (CL0222)


MviN, MATE-like superfamily Add an annotation

This superfamily consists of a variety of integral membrane protein families. The MATE family are known to be transporters. Other proteins have been implicated in virulence and polysaccharide biosynthesis.

This clan contains 8 families and the total number of domains in the clan is 127313. The clan was built by A Bateman.


This clan contains the following 8 member families:

ANKH MatE MurJ PelG Polysacc_synt Polysacc_synt_3 Polysacc_synt_C Rft-1

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
MatE (PF01554) 85504 (67.2%) View
Polysacc_synt_C (PF14667) 12144 (9.5%) View
Polysacc_synt (PF01943) 11856 (9.3%) View
MurJ (PF03023) 7439 (5.8%) View
Polysacc_synt_3 (PF13440) 7155 (5.6%) View
Rft-1 (PF04506) 2311 (1.8%) View
ANKH (PF07260) 528 (0.4%) View
PelG (PF16933) 376 (0.3%) View
Total: 8 Total: 127313 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...