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312  structures 9555  species 0  interactions 32292  sequences 235  architectures

Clan: PFL-like (CL0339)


PFL-like glycyl radical enzyme superfamily Add an annotation

The N- and C-terminal halves of the structure have similar topologies but in some cases only one is represented by the members here, viz; the C-terminal domain of the R1 subunit of ribonucleotide reductase, and the N-terminal of PFL. The full-length structure is modelled by NRDD.

This clan contains 6 families and the total number of domains in the clan is 32292. The clan was built by P Coggill.


This clan contains the following 6 member families:

DUF3029 DUF711 Gly_radical NRDD PFL-like Ribonuc_red_lgC

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Ribonuc_red_lgC (PF02867) 17644 (54.6%) View
Gly_radical (PF01228) 4469 (13.8%) View
NRDD (PF13597) 4217 (13.1%) View
PFL-like (PF02901) 4147 (12.8%) View
DUF711 (PF05167) 1575 (4.9%) View
DUF3029 (PF11230) 240 (0.7%) View
Total: 6 Total: 32292 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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