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81  structures 6992  species 0  interactions 33814  sequences 118  architectures

Clan: POTRA (CL0191)


POTRA domain superfamily Add an annotation

The polypeptide-transport-associated (POTRA) domain is predicted to be organised into three beta-strands and two alpha helices, the latter being found between strands 2 and 3. It is usually found associated with a beta-barrel outer membrane domain. It is thought to have a chaperone-like function; the proteins it is found in are involved in processes as diverse as bacterial septation and protein transport across membranes [1].

This clan contains 6 families and the total number of domains in the clan is 33814. The clan was built by M Fenech.

Literature references

  1. Sanchez-Pulido L, Devos D, Genevrois S, Vicente M, Valencia A; , Trends Biochem Sci 2003;28:523-526.: POTRA: a conserved domain in the FtsQ family and a class of beta-barrel outer membrane proteins. PUBMED:14559180 EPMC:14559180


This clan contains the following 6 member families:


Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
POTRA (PF07244) 21951 (64.9%) View
POTRA_1 (PF08478) 5923 (17.5%) View
POTRA_2 (PF08479) 2953 (8.7%) View
YqfD (PF06898) 1171 (3.5%) View
POTRA_TamA_1 (PF17243) 994 (2.9%) View
POTRA_3 (PF17287) 822 (2.4%) View
Total: 6 Total: 33814 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...