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637  structures 8641  species 0  interactions 111326  sequences 7443  architectures

Clan: PP-binding (CL0314)


ACP-like superfamily Add an annotation

This clan contains 5 families and the total number of domains in the clan is 111326. The clan was built by A Bateman.

Literature references

  1. Byers DM, Gong H; , Biochem Cell Biol. 2007;85:649-662.: Acyl carrier protein: structure-function relationships in a conserved multifunctional protein family. PUBMED:18059524 EPMC:18059524
  2. Leibundgut M, Jenni S, Frick C, Ban N; , Science. 2007;316:288-290.: Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase. PUBMED:17431182 EPMC:17431182


This clan contains the following 5 member families:

DUF1493 Fas_alpha_ACP PP-binding PP-binding_2 Ribosomal_L50

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
PP-binding (PF00550) 108801 (97.7%) View
Fas_alpha_ACP (PF18325) 1308 (1.2%) View
Ribosomal_L50 (PF10501) 862 (0.8%) View
DUF1493 (PF07377) 319 (0.3%) View
PP-binding_2 (PF14573) 36 (0.0%) View
Total: 5 Total: 111326 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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