Summary
Ribonuclease H-like superfamily
This clan includes a diverse set of nucleases that share a similar structure to Ribonuclease H.
This clan contains 70 families and the total number of domains in the clan is 481615. The clan was built by A Bateman.
Literature references
- Rice P, Craigie R, Davies DR; , Curr Opin Struct Biol. 1996;6:76-83.: Retroviral integrases and their cousins. PUBMED:8696976 EPMC:8696976
Members
This clan contains the following 70 member families:
Arena_ncap_C CAF1 DDE_1 DDE_2 DDE_3 DDE_5 DDE_Tnp_1 DDE_Tnp_1_2 DDE_Tnp_1_3 DDE_Tnp_1_4 DDE_Tnp_1_5 DDE_Tnp_1_6 DDE_Tnp_1_7 DDE_Tnp_2 DDE_Tnp_4 DDE_Tnp_IS1 DDE_Tnp_IS1595 DDE_Tnp_IS240 DDE_Tnp_IS66 DDE_Tnp_ISAZ013 DDE_Tnp_ISL3 DDE_Tnp_Tn3 Dimer_Tnp_Tn5 DNA_pol_A_exo1 DNA_pol_B_exo1 DNA_pol_B_exo2 DNA_pol_P_Exo DUF1258 DUF2779 DUF3882 DUF3892 DUF4152 DUF99 Endonuclease_5 KDZ Maelstrom Methyltransf_1N MGMT_N MULE NurA OrfB_IS605 Piwi Plant_tran Plavaka Pox_A22 Ribosomal_S30AE RNase_H RNase_H_2 RNase_HII RNase_T RNaseH_like RT_RNaseH RT_RNaseH_2 RuvC RuvC_1 Rv2179c-like rve rve_2 rve_3 RVT_3 Taq-exonuc TerL_nuclease Terminase_3C Terminase_6C Transposase_1 Transposase_21 Transposase_mut UPF0236 UvrC_RNaseH_dom Ydc2-catalytExternal database links
SCOP: | 53098 |
Domain organisation
Below is a listing of the unique domain organisations or architectures from this clan. More...
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Alignments
The table below shows the number of occurrences of each domain throughout the sequence database. More...
Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.
Family relationships
This diagram shows the relationships between members of this clan. More...
Species distribution
Tree controls
HideThis tree shows the occurrence of the domains in this clan across different species. More...
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Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.
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