Powering down the Pfam website
On October 5th, we began redirecting traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will remain available at pfam-legacy.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
90  structures 1716  species 0  interactions 77882  sequences 2588  architectures

Clan: Retroviral_zf (CL0511)


Retrovirus zinc finger-like domains Add an annotation

This superfamily has zinc-finger domains from GAG proteins, HIV nucleocapsids, nucleocapsid proteins from mason-pfizer monkey virus, and from other nucleic-acid binding proteins. Sometimes the domains appears in duplicate.

This clan contains 8 families and the total number of domains in the clan is 77882. The clan was built by P Coggill.


This clan contains the following 8 member families:

CLIP1_ZNF eIF3g zf-CCHC zf-CCHC_2 zf-CCHC_3 zf-CCHC_4 zf-CCHC_5 zf-CCHC_6

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
zf-CCHC (PF00098) 62734 (80.6%) View
zf-CCHC_2 (PF13696) 3161 (4.1%) View
zf-CCHC_4 (PF14392) 3149 (4.0%) View
CLIP1_ZNF (PF16641) 3048 (3.9%) View
zf-CCHC_3 (PF13917) 2183 (2.8%) View
eIF3g (PF12353) 1938 (2.5%) View
zf-CCHC_6 (PF15288) 1483 (1.9%) View
zf-CCHC_5 (PF14787) 186 (0.2%) View
Total: 8 Total: 77882 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...