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417  structures 9005  species 0  interactions 61531  sequences 362  architectures

Clan: TKC_like (CL0591)


Transketolase C-terminal domain-like superfamily Add an annotation

This superfamily is coposed of three branches that include the true C-terminal domains of transketolases, the C-terminal domain of the beta-subunit of branched-chain alpha-keto acid dehydrogenase, and domain II of pyruvate-ferredoxin oxidoreductase, PFOR, family.

This clan contains 4 families and the total number of domains in the clan is 61531. The clan was built by P Coggill.


This clan contains the following 4 member families:

OxoGdeHyase_C PFOR_II Transketolase_C XFP_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Transketolase_C (PF02780) 41174 (66.9%) View
OxoGdeHyase_C (PF16870) 9916 (16.1%) View
PFOR_II (PF17147) 7220 (11.7%) View
XFP_C (PF09363) 3221 (5.2%) View
Total: 4 Total: 61531 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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