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0  structures 3659  species 0  interactions 10723  sequences 52  architectures

Clan: ThrE (CL0470)


Threonine/Serine exporter ThrE superfamily Add an annotation

This superfamily includes two related families of membrane proteins, ThrE, involved in the export of threonine and serine [1]. Members of this superfamily are diverse in sequence and ubiquitous, being found in bacteria, archaea and eukaryotes [1,2].

This clan contains 2 families and the total number of domains in the clan is 10723. The clan was built by A Bateman.

Literature references

  1. Yen MR, Tseng YH, Simic P, Sahm H, Eggeling L, Saier MH Jr;, Res Microbiol. 2002;153:19-25.: The ubiquitous ThrE family of putative transmembrane amino acid efflux transporters. PUBMED:11881894 EPMC:11881894
  2. Eggeling L, Sahm H;, Arch Microbiol. 2003;180:155-160.: New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli. PUBMED:12879215 EPMC:12879215


This clan contains the following 2 member families:

ThrE ThrE_2

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
ThrE (PF06738) 5758 (53.7%) View
ThrE_2 (PF12821) 4965 (46.3%) View
Total: 2 Total: 10723 Clan alignment

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...