Powering down the Pfam website
On October 5th, we began redirecting traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will remain available at pfam-legacy.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 2008  species 0  interactions 4377  sequences 29  architectures

Clan: TrbC_VirB2 (CL0690)


TrbC/VirB2 pilin superfamily Add an annotation

This superfamily includes several pilin families that are related to the TrbC protein. TrbC is cyclised by the TraF protein and so other families may undergo a similar processing step.

This clan contains 6 families and the total number of domains in the clan is 4377. The clan was built by A Bateman.


This clan contains the following 6 member families:

DUF3852 DUF4134 Maff2 T4SS_CagC T4SS_pilin TrbC

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

Loading domain graphics...


The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
TrbC (PF04956) 2159 (49.3%) View
DUF4134 (PF13572) 764 (17.5%) View
T4SS_pilin (PF18895) 662 (15.1%) View
Maff2 (PF12750) 641 (14.6%) View
DUF3852 (PF12963) 115 (2.6%) View
T4SS_CagC (PF16943) 36 (0.8%) View
Total: 6 Total: 4377 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...