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2878  structures 342  species 0  interactions 13591  sequences 1182  architectures

Clan: Viral_Gag (CL0148)


Viral Gag protein Add an annotation

This clan contains Gag proteins which are involved in viral assembly and replication [1][2].

This clan contains 5 families and the total number of domains in the clan is 13591. The clan was built by J Mistry.

Literature references

  1. Hsu HW, Schwartzberg P, Goff SP; , Virology 1985;142:211-214.: Point mutations in the P30 domain of the gag gene of Moloney murine leukemia virus. PUBMED:2414902 EPMC:2414902
  2. Wehrly K, Chesebro B; , Methods 1997;12:288-293.: p24 antigen capture assay for quantification of human immunodeficiency virus using readily available inexpensive reagents. PUBMED:9245608 EPMC:9245608


This clan contains the following 5 member families:

Gag_p24 Gag_p24_C Gag_p30 Gag_spuma SCAN

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
SCAN (PF02023) 9488 (69.8%) View
Gag_p30 (PF02093) 1547 (11.4%) View
Gag_p24 (PF00607) 1354 (10.0%) View
Gag_p24_C (PF19317) 1182 (8.7%) View
Gag_spuma (PF03276) 20 (0.1%) View
Total: 5 Total: 13591 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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