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36  structures 1583  species 0  interactions 45295  sequences 701  architectures

Clan: Vps51 (CL0295)


Vps51 domain superfamily Add an annotation

This clan includes an N-terminal domain from several vesicle transport proteins that are related to Vps51.

This clan contains 18 families and the total number of domains in the clan is 45295. The clan was built by A Bateman.


This clan contains the following 18 member families:

COG2 COG5 COG6 Dor1 Dsl1_N Exo70 Exo84_C Sec15 Sec3_C Sec3_C_2 Sec5 Sec6 Sec8_exocyst Vps51 Vps52 Vps53_N Vps54_N Zw10

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Exo70 (PF03081) 7044 (15.6%) View
Vps51 (PF08700) 4671 (10.3%) View
Sec6 (PF06046) 3802 (8.4%) View
Sec3_C (PF09763) 3293 (7.3%) View
Sec15 (PF04091) 3135 (6.9%) View
Sec5 (PF15469) 2917 (6.4%) View
Vps52 (PF04129) 2538 (5.6%) View
Vps53_N (PF04100) 2467 (5.4%) View
Vps54_N (PF10475) 2366 (5.2%) View
Dor1 (PF04124) 2168 (4.8%) View
COG6 (PF06419) 2147 (4.7%) View
Exo84_C (PF16528) 2010 (4.4%) View
Sec8_exocyst (PF04048) 1792 (4.0%) View
COG2 (PF06148) 1733 (3.8%) View
COG5 (PF10392) 1599 (3.5%) View
Zw10 (PF06248) 1580 (3.5%) View
Dsl1_N (PF11988) 30 (0.1%) View
Sec3_C_2 (PF15278) 3 (0.0%) View
Total: 18 Total: 45295 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

Loading structure mapping...