Summary

Zinc beta-ribbon

A clan of zinc-binding ribbon domains.

This clan contains 89 families and the total number of domains in the clan is 434792. The clan was built by RD Finn.

Literature references

Grishin NV; , J Mol Biol 2000;299:1165-1177.: C-terminal domains of Escherichia coli topoisomerase I belong to the zinc-ribbon superfamily. PUBMED:10873443 EPMC:10873443

Members

This clan contains the following 89 member families:

A2L_zn_ribbon Auto_anti-p27 Baculo_LEF5_C CpXC DNA_RNApol_7kD DUF1451 DUF1936 DUF2072 DUF2116 DUF2180 DUF2387 DUF2614 DUF35_N DUF3945 DUF4379 DUF6574 DZR DZR_2 Elf1 GATA HVO_2753_ZBP Lar_restr_allev LIM MscL Mu-like_Com NinF NOB1_Zn_bind Nudix_N_2 Ogr_Delta OrfB_Zn_ribbon PriA_CRR Prim_Zn_Ribbon RecO_C Ribosomal_L32p Ribosomal_L33 Ribosomal_L37ae Ribosomal_L37e Ribosomal_L40e Ribosomal_L44 Ribosomal_S27 Ribosomal_S27e RNA_POL_M_15KD Rubredoxin_2 Spt4 Stc1 TF_Zn_Ribbon TFIIS_C Tnp_zf-ribbon_2 Topo_Zn_Ribbon Toprim_Crpt Trm112p UPF0547 YjdM_Zn_Ribbon zf-C4 zf-C4_ClpX zf-C4_Topoisom zf-CHC2 zf-CSL zf-dskA_traR zf-FPG_IleRS zf-GRF zf-ISL3 zf-NADH-PPase zf-PARP zf-RanBP zf-ribbon_3 zf-RING_7 zf-RRN7 zf-TFIIB zf-trcl zf-ZPR1 zf_PR_Knuckle zf_Rg zinc-ribbon_6 zinc-ribbons_6 zinc_ribbon_10 zinc_ribbon_11 zinc_ribbon_12 zinc_ribbon_13 zinc_ribbon_15 zinc_ribbon_2 zinc_ribbon_4 zinc_ribbon_5 zinc_ribbon_9 Zn-ribbon_8 Zn_ribbon_recom Zn_ribbon_SprT Zn_Tnp_IS1 Zn_Tnp_IS1595

External database links

SCOP:

57783

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family	Num. domains	Alignment
LIM (PF00412)	106776 (24.6%)	View
zf-C4 (PF00105)	32435 (7.5%)	View
zf-RanBP (PF00641)	23716 (5.5%)	View
GATA (PF00320)	22653 (5.2%)	View
zf-C4_Topoisom (PF01396)	14012 (3.2%)	View
zf-FPG_IleRS (PF06827)	11667 (2.7%)	View
OrfB_Zn_ribbon (PF07282)	11226 (2.6%)	View
zf-CHC2 (PF01807)	10103 (2.3%)	View
zf-dskA_traR (PF01258)	9978 (2.3%)	View
Ribosomal_L33 (PF00471)	9906 (2.3%)	View
Ribosomal_L32p (PF01783)	9431 (2.2%)	View
Rubredoxin_2 (PF18073)	8679 (2.0%)	View
zf-GRF (PF06839)	8641 (2.0%)	View
Zn_ribbon_recom (PF13408)	8172 (1.9%)	View
zf-C4_ClpX (PF06689)	8113 (1.9%)	View
TFIIS_C (PF01096)	7483 (1.7%)	View
RecO_C (PF02565)	7469 (1.7%)	View
MscL (PF01741)	6863 (1.6%)	View
Trm112p (PF03966)	5902 (1.4%)	View
PriA_CRR (PF18319)	5835 (1.3%)	View
DUF35_N (PF12172)	4801 (1.1%)	View
TF_Zn_Ribbon (PF08271)	4735 (1.1%)	View
Zn-ribbon_8 (PF09723)	4681 (1.1%)	View
zinc_ribbon_2 (PF13240)	4674 (1.1%)	View
zf-NADH-PPase (PF09297)	4654 (1.1%)	View
zf-ZPR1 (PF03367)	3920 (0.9%)	View
zf-PARP (PF00645)	3738 (0.9%)	View
DZR (PF12773)	3406 (0.8%)	View
Ribosomal_S27e (PF01667)	3151 (0.7%)	View
RNA_POL_M_15KD (PF02150)	3097 (0.7%)	View
zf-CSL (PF05207)	2975 (0.7%)	View
zf-ISL3 (PF14690)	2754 (0.6%)	View
Ribosomal_L37ae (PF01780)	2705 (0.6%)	View
Ribosomal_L44 (PF00935)	2687 (0.6%)	View
zinc_ribbon_9 (PF14369)	2595 (0.6%)	View
DZR_2 (PF18912)	2477 (0.6%)	View
zf-RING_7 (PF02591)	2316 (0.5%)	View
Ribosomal_L37e (PF01907)	2313 (0.5%)	View
zf-TFIIB (PF13453)	2206 (0.5%)	View
Ribosomal_S27 (PF01599)	2184 (0.5%)	View
YjdM_Zn_Ribbon (PF08274)	2030 (0.5%)	View
Ribosomal_L40e (PF01020)	2003 (0.5%)	View
Toprim_Crpt (PF13342)	1990 (0.5%)	View
Spt4 (PF06093)	1988 (0.5%)	View
Elf1 (PF05129)	1969 (0.5%)	View
continued

Pfam family	Num. domains	Alignment
zinc_ribbon_10 (PF10058)	1923 (0.4%)	View
NOB1_Zn_bind (PF08772)	1680 (0.4%)	View
DUF4379 (PF14311)	1596 (0.4%)	View
Nudix_N_2 (PF14803)	1581 (0.4%)	View
DNA_RNApol_7kD (PF03604)	1581 (0.4%)	View
Zn_Tnp_IS1595 (PF12760)	1576 (0.4%)	View
zinc_ribbon_4 (PF13717)	1377 (0.3%)	View
Topo_Zn_Ribbon (PF08272)	1361 (0.3%)	View
Zn_ribbon_SprT (PF17283)	1341 (0.3%)	View
Auto_anti-p27 (PF06677)	1176 (0.3%)	View
zinc_ribbon_12 (PF11331)	1083 (0.2%)	View
zinc-ribbon_6 (PF10005)	1058 (0.2%)	View
zf-trcl (PF13451)	978 (0.2%)	View
zinc_ribbon_15 (PF17032)	962 (0.2%)	View
zf-RRN7 (PF11781)	836 (0.2%)	View
DUF3945 (PF13101)	826 (0.2%)	View
zf-ribbon_3 (PF13248)	654 (0.2%)	View
zinc_ribbon_5 (PF13719)	624 (0.1%)	View
DUF2387 (PF09526)	589 (0.1%)	View
DUF1451 (PF07295)	582 (0.1%)	View
Prim_Zn_Ribbon (PF08273)	554 (0.1%)	View
Zn_Tnp_IS1 (PF03811)	521 (0.1%)	View
UPF0547 (PF10571)	513 (0.1%)	View
zinc_ribbon_13 (PF09855)	500 (0.1%)	View
Stc1 (PF12898)	488 (0.1%)	View
DUF2614 (PF11023)	465 (0.1%)	View
Tnp_zf-ribbon_2 (PF13842)	421 (0.1%)	View
Ogr_Delta (PF04606)	416 (0.1%)	View
zf_PR_Knuckle (PF18445)	366 (0.1%)	View
CpXC (PF14353)	300 (0.1%)	View
Lar_restr_allev (PF14354)	268 (0.1%)	View
DUF2072 (PF09845)	247 (0.1%)	View
HVO_2753_ZBP (PF07754)	230 (0.1%)	View
zinc-ribbons_6 (PF07191)	183 (0.0%)	View
DUF2116 (PF09889)	150 (0.0%)	View
Mu-like_Com (PF10122)	133 (0.0%)	View
DUF2180 (PF09947)	131 (0.0%)	View
A2L_zn_ribbon (PF08792)	100 (0.0%)	View
zf_Rg (PF17915)	96 (0.0%)	View
DUF6574 (PF20214)	86 (0.0%)	View
NinF (PF05810)	74 (0.0%)	View
Baculo_LEF5_C (PF11792)	28 (0.0%)	View
zinc_ribbon_11 (PF11682)	25 (0.0%)	View
DUF1936 (PF09151)	4 (0.0%)	View
Total: 89	Total: 434792	No alignment ℹ

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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Clan: Zn_Beta_Ribbon (CL0167)

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