# STOCKHOLM 1.0
#=GF ID   Ndufs5
#=GF AC   PF10200.12
#=GF DE   NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
#=GF AU   KOGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   KOGs (KOG4110)
#=GF GA   21.20 21.20;
#=GF TC   21.20 21.20;
#=GF NC   21.10 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   NADH_dehydrogenase_(ubiquinone)
#=GF CL   CL0351
#=GF RN   [1]
#=GF RM   10070614
#=GF RT   The human NADH: ubiquinone oxidoreductase NDUFS5 (15 kDa)
#=GF RT   subunit: cDNA cloning, chromosomal localization, tissue
#=GF RT   distribution and the absence of mutations in isolated complex
#=GF RT   I-deficient patients. 
#=GF RA   Loeffen J, Smeets R, Smeitink J, Triepels R, Sengers R, Trijbels
#=GF RA   F, van den Heuvel L; 
#=GF RL   J Inherit Metab Dis. 1999;22:19-28.
#=GF DR   INTERPRO; IPR019342;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of short, approximately 105 amino acid residue,
#=GF CC   proteins which form part of NADH:ubiquinone oxidoreductase
#=GF CC   complex I. Complex I is the first multisubunit inner membrane
#=GF CC   protein complex of the mitochondrial electron transport chain
#=GF CC   and it transfers two electrons from NADH to ubiquinone. The
#=GF CC   protein carries four highly conserved cysteine residues but
#=GF CC   these do not appear to be in a configuration which would favour
#=GF CC   metal binding so the exact function of the protein is uncertain
#=GF CC   [1].
#=GF SQ   5
#=GS NDUS5_MOUSE/1-96   AC Q99LY9.3
#=GS NDUS5_MOUSE/1-96   DR PDB; 7AK6 e; 1-95;
#=GS NDUS5_MOUSE/1-96   DR PDB; 7AK5 e; 1-95;
#=GS NDUS5_MOUSE/1-96   DR PDB; 6ZTQ e; 1-95;
#=GS NDUS5_MOUSE/1-96   DR PDB; 6G72 e; 1-95;
#=GS NDUS5_MOUSE/1-96   DR PDB; 6ZR2 e; 1-95;
#=GS NDUS5_PANTR/1-96   AC Q0MQH4.3
#=GS NDUS5_BOVIN/1-96   AC Q02379.2
#=GS NDUS5_BOVIN/1-96   DR PDB; 5LC5 e; 6-94;
#=GS NDUS5_BOVIN/1-96   DR PDB; 5LDX e; 6-94;
#=GS NDUS5_BOVIN/1-96   DR PDB; 5LDW e; 6-94;
#=GS Q502P6_DANRE/1-96  AC Q502P6.1
#=GS H3CN98_TETNG/1-96  AC H3CN98.1
NDUS5_MOUSE/1-96              MPFLDIQKKLGISLDRHFMFLSAEQPYKNAARCHAFEKEWIECAHGIGGTRAKKECKIEFDDFEECLLRYKTMRRMHDIKKQREKLMKEGKYTPPP
#=GR NDUS5_MOUSE/1-96   SS    X--S-HHHHHT--SSTTSSBSSS--SSS---TTHHHHHHHHHHSSSSTCGGHHHHSHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHHHHTS----H
NDUS5_PANTR/1-96              MPFLDIQKRFGLNIDRWLTIQSGEQPYKMAGRCHAFEKEWIECAHGIGYTRAEKECKIEYDDFVECLLRQKTMRRAGTIRKQRDKLIKEGKYTPPP
NDUS5_BOVIN/1-96              MPFFDVQKRLGVDLDRWMTIQSAEQPHKIPSRCHAFEKEWIECAHGIGSIRAEKECKIEFEDFRECLLRQKTMKRLHAIRRQREKLIKEGKYTPPP
#=GR NDUS5_BOVIN/1-96   SS    XXXXXX--S---SS-----SSS-S-SSS---TTHHHHHHHHHHSSSHHHHTTTSTTHHHHHHHHHHHT-HHHHHHHHHHHHHHHH-TTSS-----X
Q502P6_DANRE/1-96             MPFIDLQSKLGINVDKWLLAQSGEQPRKRAAFCHAFEKEWIECSHAIGKTRASKECNIEWEDFYECMHRFKTMKRLKEISTQKEKMIKEGTYTPPP
H3CN98_TETNG/1-96             MPFVDLNKRLGVNLDHWILTQSGPQPHQRAARCHVFEKEWIECSHGIGQTRAKKECQLEFEDFYECLHRQKTHQRLQAIRQQRDKMVKEGTYTPPP
#=GC SS_cons                  XXXSXHHHCHT-SSSTTSSCSSSS-SSS---TTHHHHHHHHHHSSSCCCHCCCCCTHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHCCCTS----H
#=GC seq_cons                 MPFlDlQKRLGlNLDRWlhhQSGEQP+KpAARCHAFEKEWIECAHGIGpTRAcKECKIEFEDFhECLLRQKTM+RL+sIR+QREKLIKEGKYTPPP
//