# STOCKHOLM 1.0
#=GF ID   pYEATS
#=GF AC   PF20305.1
#=GF DE   prokaryotic YEATS domain
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Aravind L
#=GF GA   26.90 26.90;
#=GF TC   26.90 26.90;
#=GF NC   26.80 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0154
#=GF RN   [1]
#=GF RM   32868406
#=GF RT   Identification of Uncharacterized Components of Prokaryotic
#=GF RT   Immune Systems and Their Diverse Eukaryotic Reformulations.
#=GF RA   Burroughs AM, Aravind L;
#=GF RL   J Bacteriol. 2020; [Epub ahead of print]
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a prokaryotic YEATS domain. pYEATS is
#=GF CC   fused to diverse effector domains, suggesting that the binding
#=GF CC   to a ligand activates an effector-based response against an
#=GF CC   invasive threat. It has been predicted to specifically recognise
#=GF CC   invader-induced modifications of macromolecules by acyl moieties
#=GF CC   (e.g. phage-encoded acylations of surface polysaccharides) to
#=GF CC   unleash the fused effectors through a conformational change [1].
#=GF SQ   58
#=GS A0A315ZBE7_9BACT/96-170     AC A0A315ZBE7.1
#=GS F2IFK4_FLUTR/315-386        AC F2IFK4.1
#=GS H1YBZ3_9SPHI/303-373        AC H1YBZ3.1
#=GS A0A5C6DJE3_9BACT/223-298    AC A0A5C6DJE3.1
#=GS D8FFP3_9DELT/472-547        AC D8FFP3.1
#=GS A0A2T4UZZ8_9DELT/65-140     AC A0A2T4UZZ8.1
#=GS H0I105_9RHIZ/47-122         AC H0I105.1
#=GS A0A1H8TUQ7_9SPHI/41-116     AC A0A1H8TUQ7.1
#=GS A0A0M8MFE3_9FLAO/402-476    AC A0A0M8MFE3.1
#=GS A0A2S1QXU6_9FLAO/413-487    AC A0A2S1QXU6.1
#=GS A0A0D2JRW3_9DELT/31-107     AC A0A0D2JRW3.1
#=GS A0A1H4GLD9_9BACT/119-192    AC A0A1H4GLD9.1
#=GS A0A2P8HUV5_9BACT/16-89      AC A0A2P8HUV5.1
#=GS A0A5C6A0B4_9BACT/207-286    AC A0A5C6A0B4.1
#=GS A0A561EHP3_9ACTN/131-204    AC A0A561EHP3.1
#=GS A0A077M6C1_9MICO/121-201    AC A0A077M6C1.1
#=GS A0A0D1MS06_BRAEL/17-89      AC A0A0D1MS06.1
#=GS A0A068NJT4_9BACT/2203-2275  AC A0A068NJT4.1
#=GS D8P7M7_9BACT/222-294        AC D8P7M7.1
#=GS A0A1G9RB69_9FLAO/23-95      AC A0A1G9RB69.1
#=GS L0DWS9_THIND/17-89          AC L0DWS9.1
#=GS A0A1Q4Y3I8_9ACTN/298-371    AC A0A1Q4Y3I8.1
#=GS A0A0F4K5F5_9ACTN/105-179    AC A0A0F4K5F5.1
#=GS A0A4Q7KJ54_9PSEU/117-191    AC A0A4Q7KJ54.1
#=GS A0A429Z2K6_9RHIZ/33-105     AC A0A429Z2K6.1
#=GS A0A1H5J6B6_9FLAO/44-116     AC A0A1H5J6B6.1
#=GS A0A238VT50_9FLAO/39-112     AC A0A238VT50.1
#=GS A0A0N9I315_9PSEU/127-202    AC A0A0N9I315.1
#=GS A0A401FTY8_9DELT/469-542    AC A0A401FTY8.1
#=GS A0A285Z240_9BACT/37-103     AC A0A285Z240.1
#=GS A0A1E3X4D0_9BACT/186-268    AC A0A1E3X4D0.1
#=GS A0A1I0X758_9BACT/579-652    AC A0A1I0X758.1
#=GS A0A3B0C0Z3_9FLAO/558-628    AC A0A3B0C0Z3.1
#=GS A0A5C6ZED2_9FLAO/574-648    AC A0A5C6ZED2.1
#=GS G7WKS8_METH6/261-331        AC G7WKS8.1
#=GS A6G2X2_9DELT/257-329        AC A6G2X2.1
#=GS A0A142HGI1_9BACT/301-373    AC A0A142HGI1.1
#=GS A0A0J6NLX2_9NEIS/544-614    AC A0A0J6NLX2.1
#=GS A0A1M4ZUQ1_9RHIZ/152-223    AC A0A1M4ZUQ1.1
#=GS A0A255Z1E2_9SPHN/435-501    AC A0A255Z1E2.1
#=GS A0A257GHY9_9RHOB/584-650    AC A0A257GHY9.1
#=GS A0A370KZ76_9BRAD/389-456    AC A0A370KZ76.1
#=GS B0UD07_METS4/272-346        AC B0UD07.1
#=GS A0A085EF71_9FLAO/305-378    AC A0A085EF71.1
#=GS M7XDC6_9BACT/273-345        AC M7XDC6.1
#=GS A0A5N1INE8_9BACT/325-394    AC A0A5N1INE8.1
#=GS A0A0E9N359_9BACT/323-394    AC A0A0E9N359.1
#=GS A0A286IN77_9BACT/269-337    AC A0A286IN77.1
#=GS A0A2R7KMH9_9SPHI/357-424    AC A0A2R7KMH9.1
#=GS A0A0Q0UYQ3_9SPHI/302-371    AC A0A0Q0UYQ3.1
#=GS A0A1K1RCI2_9GAMM/367-437    AC A0A1K1RCI2.1
#=GS A0A4Q2URW5_9BACT/225-294    AC A0A4Q2URW5.1
#=GS A6GGI8_9DELT/28-100         AC A6GGI8.1
#=GS A1SVT0_PSYIN/30-102         AC A1SVT0.1
#=GS A0A0L1JQI4_9RHOB/33-107     AC A0A0L1JQI4.1
#=GS K2KFM9_9GAMM/30-102         AC K2KFM9.1
#=GS A0A4V3D7P7_9GAMM/160-234    AC A0A4V3D7P7.1
#=GS B3PF04_CELJU/159-232        AC B3PF04.1
A0A315ZBE7_9BACT/96-170                YLFSIWVSS........DPDVME.EIE.SVHYVFNHGS..F.EI..KGRTGT....DLSDG...FKVSYQG.WGCLTL.VEIIIRYKNNAEEDLFFNMC
F2IFK4_FLUTR/315-386                   IDYGLNIAA..........NVQP.LVD.RVTYVYDHSA..F.....PNKYIT...VSSGPH...YQTSYEGPYCLPNM.QAIVY.LKDGKSIKVEFNGC
H1YBZ3_9SPHI/303-373                   YDVTLNVINA.......SNNPID.....SVQYFL.HYT..M.EH..PVLTMT....NPEQD...FYLSMAL.WGTFPI.KAKVF.FADGKVYDLYKNFD
A0A5C6DJE3_9BACT/223-298               WDWTIFVKG........PEDVLE.KIE.YVEYTL.HPT..F.NN..PVRIIN....ERGHGPYAFPLSTSG.WGTFTV.KVKVY.YKDGTYQRMAHSLK
D8FFP3_9DELT/472-547                   WDWTVFIRA........SRDVLE.QIN.CVEYTL.HPT..F.PN..PVRTVC.RKGSPDRP...FALSSNG.WGTFTI.DIRVM.MKNGQEKKLQHALR
A0A2T4UZZ8_9DELT/65-140                WRWTVYIQA........PKDVLQ.RVK.CVEYVL.DRT..F.PD..PIREVC.DRGTGAQA...FPLKVTA.WGPSTV.RIRVR.FLDGRVQELEHELT
H0I105_9RHIZ/47-122                    FEWTAYVVA........DDSELR.NIK.CVVYTL.HPT..F.PD..PVQRIC.DTDNPRYP...FGLTVSG.WGSFNL.RTKIE.FKNGSSKEVVHRVD
A0A1H8TUQ7_9SPHI/41-116                KSWKVFVIG........NPQFIK.SIK.QIDYTL.DGT..YGQQ..HIVVIN...NGDNPF...FTMCNKG.WGEIYI.KIRISYNNGLADTFESYRVD
A0A0M8MFE3_9FLAO/402-476               FEARAWIASHW......EQKQDE.QLV.KVEWSA.GPK..FKKK..QIANFD.....TNPN...FCIAYQY.YGPMVI.EAKMT.FADKYTATAFVYAH
A0A2S1QXU6_9FLAO/413-487               YEARGWIVQHK......PELYKGSLLE.KVEWTA.GEY..F..K..KIICLR....DDNPN...FSFSYHY.WGPMLI.QAKMF.FNDKSEAICYVYAR
A0A0D2JRW3_9DELT/31-107                ADIVIWLQQHG......KGPLSDGQIE.KVEYQL.GNK..FFKE..PKVKIN.....AADA...FRLEVSA.YGPMLS.VARIYIKNDPTSLILKRYIN
A0A1H4GLD9_9BACT/119-192               YDLLIYVIP........HNNSTLIQVK.SVEYFL.GPH..W.NN..QVFKTR....DRSKG...FAIKTSA.FGEFLC.TTKII.FTDGQEITINRYID
A0A2P8HUV5_9BACT/16-89                 YDLLIYVIP........HNEASLIQVK.SVEYFL.GPF..W.GN..QVFKTK....NRSKG...FAVKTSA.YGEFLC.TAKIT.FTDNQEMFVHRYID
A0A5C6A0B4_9BACT/207-286               YDILIYLFRHRPDNAGSPFGLDD..VT.KAEFLL.GPS..W.KN..RVFACD..N..DGGY...IGIKVSA.FGTFLC.LCRVT.FANGETAILDRYID
A0A561EHP3_9ACTN/131-204               FDVFVYLVT........SRTGSLDEVE.RAQFFL.GRR..W.GN..RVFDVL....NEGGR...IGFSTAA.YGSPLC.ACRVV.FKDGSDVVLSRFLD
A0A077M6C1_9MICO/121-201               CDLFVFLTGWRRSAYGLPDDLSD..VS.TAEFYL.GPN..FEPS..GTTVTR....RHGST...LGFVTSA.WGPVIC.ACRVT.FTDGDQVILSRYLD
A0A0D1MS06_BRAEL/17-89                 WRWHAWIES........GNTELD.KVK.EVVWIL.HPS..F.RQ..PRVVSK....DRADK...FRLSTAG.WGTFVL.RAEVM.LSDAKKVLLKHNVE
A0A068NJT4_9BACT/2203-2275             FRWRLFLDE........SPEFVQ.SVR.SVRYIL.HDS..F.AL..SVRMTT....DASTD...FSLRSEG.WGTFEV.RMIIT.FRDGTQVAASHHLS
D8P7M7_9BACT/222-294                   YEWRVFVDE........PDSVLQ.SIK.EVQYVL.HPT..F.LE..PLQVSR....DATKQ...FELVTSG.WGQFTI.LITIV.YRDGTREKASYYLD
A0A1G9RB69_9FLAO/23-95                 FEWSIWIE.........NGELDVSEID.YVEYLL.HRT..F.KN..RLRKVT....DVSTG...FKLNSKG.WGEFRI.EISII.KKNRETIQMAHWLV
L0DWS9_THIND/17-89                     WRWSVWLDG.........SPAELDDVS.HVVYTL.HPT..F.PT..PVRHTD....DRSSD...FRISSAG.WGEFEI.FAEVT.LKSGETLKRHHWLT
A0A1Q4Y3I8_9ACTN/298-371               HHVRVFLDG.........TATDLGQVT.KVVYHL.HPT..F.PR..PERQIA....DRSTG...FALELKA.WGQFTI.TADIFTADSLIPTRLERYIS
A0A0F4K5F5_9ACTN/105-179               FRLRIALEG........DSDADLDRVA.KVVYHL.HPT..F.RD..PDRVVT....NRSTS...FELTTAA.WGMFDL.TADVYVKGSSEPIRLERYLN
A0A4Q7KJ54_9PSEU/117-191               YSIRVFLES........DNENDLDRVN.KVVYHL.HPT..F.YE..PDRTVV....DRETN...FELRTAG.WGMFNL.TAEVHLADRVEPLRLERYIN
A0A429Z2K6_9RHIZ/33-105                YKVHIYLDG........NDVL...FVN.SATYHL.HQT..F.DQ..PVRTIS..RSIRNPN...CSLAIWT.WGIFTV.KVIVE.DKSGQKYEFVHPLT
A0A1H5J6B6_9FLAO/44-116                YKVYLFIEG...........KDLPFIK.KVKYTL.HKT..F.RN..PVKTIE..RKSDNTN...CSLVIWT.WGLFNI.KVELE.DINGEIIHMNHYLN
A0A238VT50_9FLAO/39-112                YKVKIYIDG...........LDLPYIK.QVTYKL.HST..FGKNRVNIIKRT....PSNLK...CGLTIWT.WGIFTV.NAEIE.DLKGRIIQLEHRLT
A0A0N9I315_9PSEU/127-202               YQFEVIVIA........PDDVLR.RVV.SVRYEL.EKA..W.PEHLRVRTVA....DRATR...FKLKELA.NGTSIV.TARIDLRGQDQPLLLNRFID
A0A401FTY8_9DELT/469-542               YAFHAVIDA........PREILN.QIN.SVTYYL.HPS..Y.PN..PVRIVT....DMSTR...FKLKELA.WASSTL.KAEVRLRNQEEPVRLSRHIT
A0A285Z240_9BACT/37-103                YKVRLFVDT........QNPEVQ.....NVTYKL.DPT..Y.YD..PVRESR....DADRN...FEVSLST.YGDYPV.TVEAQ....VGGEIVRYTAP
A0A1E3X4D0_9BACT/186-268               YKLTYRVSVNPAAATVAEKPVMD.WIE.RVEYKF.SER..WFYN..PRMTSE....DRTKS...FEVDINV.WGRTNV.LVEIYLKGVEKPIDRENMMS
A0A1I0X758_9BACT/579-652               NNFTFWLDV........PSFRKEEIM..EVRYNF.CQG..F.YD..RVRVSK....DPTSS...FSIGYLG.WGVCPTMKIDVV.LQTGDTIPINFPFK
A0A3B0C0Z3_9FLAO/558-628               Y..LMWIDV........PSFRKL.EIQ.EVHYYF.CPG..F.IN..RRRIST....EPTSS...FSIGYLG.YGYCPG.GYDIN.IILKTGDTIHRNLP
A0A5C6ZED2_9FLAO/574-648               RNYMLWVDV.........PSFRKYEIK.QVNYKL.CSG..F.VD..RLRVSN....EPSSS...FSIGYLG.YGYCPIIDIDVILQTGDTIKKVFSFED
G7WKS8_METH6/261-331                   FRIKVLVTG........PDLY...RIR.SVHYQL.HPT..F.SP..SEQTMT....NPRDN...FELELWT.WGAFNM.PITVT.MTDGRAYRYDYRFT
A6G2X2_9DELT/257-329                   WLDQVEVRALH......PTPGCADQLD.SVTYTL.HPT..F.AD..PVETLD.......GD...AALTLYT.WGSFDA.TVKVR.LDDGGSVTFVDRVS
A0A142HGI1_9BACT/301-373               YVIQAQVTGTA......ARPLQV.....KVVLLL.HPT..F.SE..RAVEVLVDQRPAGGR...ATYSFAA.RGSFTL.VAMAD....DGDTLLGYNLA
A0A0J6NLX2_9NEIS/544-614               VTIILTVEA........ERSAKIGLGD.SAWFVL.HPT..F.SP..SALKVT....FRGNR...ARLRIQA.WGGFTV.GVWLS....KAGIELECDLT
A0A1M4ZUQ1_9RHIZ/152-223               VRVNLFVKG........DPTTESLKAGEYVEFFL.HDT..F.VP..DVFRTP....FIGNT...STLSVLA.FGGFTV.GAWIP....SREVELELDLA
A0A255Z1E2_9SPHN/435-501               TRIRLTIAG........PARDGE.....LARFYV.HDS..F.VP..PELEGS....FLKGR...ASVEVTA.WGGFTV.GGWIP....SAKLELELDLA
A0A257GHY9_9RHOB/584-650               TRINMFVEG........PALDGD.....EVLFYL.HDS..F.PK..NVWRER....FRSGS...ARLPVTA.WGGFTV.GIWIP....RQRIELELDLA
A0A370KZ76_9BRAD/389-456               VEFDLVVKGSG......KRRLRE.....SVRFHY.HPT..F.DP..RSEVVE...PSAQGE...VRTTLRA.VGAFTV.GAITE......NTRLELDLA
B0UD07_METS4/272-346                   AAFTLVVES........RPGAGPPLAG.PVRFHL.HPT..F.PR..EQVVVP....ARNGT...AELPIDFAYGAFTV.GAVVE.NDPPDENRLELDLS
A0A085EF71_9FLAO/305-378               YKVKLQIISTD......QKNNPLKNGE.ILLFAL.HNT..FGDP..PFQLVK....VEKQV...AELNFYS.SGSFTV.GAFAD....NGATELELDLA
M7XDC6_9BACT/273-345                   YEVTLEVSSTD......PVQHPLFDGE.IVIFAL.HPS..F.KP..EVRLVK....VVEGV...SRLKLIA.YGSFTV.GVFAD....SAGTELELDLS
A0A5N1INE8_9BACT/325-394               FNVHLKLES........INENNP.LSG.VAKFYL.HDS..F.RE..PVYPAN....VIDGK...AALDLTT.FGAFTV.GVIAD....GGETKLELDLK
A0A0E9N359_9BACT/323-394               FDIRIRVYA.D......EN.SPT.LKG.WVAFFV.HDSLGF.KN..DTVYAK.V..NEKGI...AEIPLVA.YEAFTA.GALTE.....DGTELEIDLN
A0A286IN77_9BACT/269-337               FELLIEVTA.F......EPDSNF.KTD..IIVFL.DRT..F.PT..NTLYLK....PTGRT...VSVKVIA.YEAFTI.GALVN.....NEVELELDLQ
A0A2R7KMH9_9SPHI/357-424               FNVILNLKVSD......PDKREQ.....FVAFFL.HDS..F.SN..EIRFKS....TKNGS...AKLEVRS.YEAFTV.GAYTE.....KGIMLELDLN
A0A0Q0UYQ3_9SPHI/302-371               FNINLSVTS........TDPNQP.LVG.EVVFNL.HPS..F.MN..EVQKVK....VLDGV...AQYNIIG.WGAFTV.GVECD....EGKTKLELDLA
A0A1K1RCI2_9GAMM/367-437               VDVVLAVRS........TDPLNDPLKG.KVTFYL.HPT..F.FE..PVIKVE....AVNSK...AQTEIRT.ADAFVV.GVECD....DGRTVLELDLS
A0A4Q2URW5_9BACT/225-294               FAVHLQVTA........PDSVQLPADA.IVVFHL.HDS..F.TP..DEHRVM....FQQRA...ATLALYA.WGAFTV.GAEAP.....GGIHLELDLA
A6GGI8_9DELT/28-100                    YNVRVYVDG........SDEELR.RVE.AVTYEL.HPS..F.RN..PVHRQT....NRASQ...FELTLWV.WGMFDI.EVEFE.LVDGGRARTRYYLR
A1SVT0_PSYIN/30-102                    FHLGVWVDA........PERELD.EIE.FVEYAL.HPT..F.KK..QNRRSL....NRLNN...FSITFWT.WGIFNI.KVAIH.LHSGEIINMDYYLE
A0A0L1JQI4_9RHOB/33-107                YHIGVWIES........DDPELMDRVS.HVEYTL.HPS..F.PN..RERRSE....NRRND...FSITFWA.WGRFDV.EARVFVEGEAEPFRITHRLN
K2KFM9_9GAMM/30-102                    YHLGVWIDG........EERDLD.QIS.FVEYRL.HST..F.TN..PLRRSA....NRRNN...FSITFWT.WGMFQI.EVTLH.LHNGQTQRLSHNLA
A0A4V3D7P7_9GAMM/160-234               YRVRVWLESFA......EQNMLK.DVA.SVTYQV.WED..F.PT..SSLSTS....DRASN...FDLWLNI.YGEFPV.LAMVK.MKDGNTIELQRYLD
B3PF04_CELJU/159-232                   YRVRVWLES........IEHRSLSDIE.SVTYHV.WDD..F.NQ..SVISTA....DASSN...FDLWLSI.YGEFPV.LALVK.TKEGQTYELQRYID
#=GC seq_cons                          aclplalpu........ssph...plp.pVpYhL.Hso..F..s..sltpss....stsss...aplshtu.aGsFsl.tsplp.htsspphclph.Ls
//