# STOCKHOLM 1.0
#=GF ID   SWI-SNF_Ssr4_C
#=GF AC   PF20497.1
#=GF DE   SWI/SNF and RSC complexes subunit Ssr4 C-terminal
#=GF AU   Wood V;0000-0001-6330-7526
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Wood V
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.00;
#=GF NC   21.90 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   33263569
#=GF RT   The X-ray crystal structure of the N-terminal domain of Ssr4, a
#=GF RT   Schizosaccharomyces pombe chromatin-remodelling protein.
#=GF RA   Newman J, Nebl T, Van H, Peat TS;
#=GF RL   Acta Crystallogr F Struct Biol Commun. 2020;76:583-589.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the C-temrinal domain of Ssr4 (SWI/SNF and
#=GF CC   RSC complexes subunit ssr4), an essential component of the
#=GF CC   chromatin-remodelling SWI/SNF and RSC (remodelling the structure
#=GF CC   of chromatin) complexes only found in S. pombe [1]. This domain
#=GF CC   contains a conserved RYxxxHEWMEEI/V motif. RSC is involved in
#=GF CC   transcription regulation and nucleosome positioning which
#=GF CC   controls, particularly, membrane and organelle development
#=GF CC   genes. The ATP-dependent chromatin remodelling complex SWI/SNF
#=GF CC   is required for the positive and negative regulation of gene
#=GF CC   expression of a large number of genes through the regulation of
#=GF CC   nucleosome remodelling.
#=GF SQ   28
#=GS C9SIJ2_VERA1/280-735      AC C9SIJ2.1
#=GS E3Q6J3_COLGM/263-717      AC E3Q6J3.1
#=GS T0K1F7_COLGC/266-713      AC T0K1F7.1
#=GS N4W4X5_COLOR/266-721      AC N4W4X5.1
#=GS C7YKL5_FUSV7/261-710      AC C7YKL5.1
#=GS I1RC12_GIBZE/261-698      AC I1RC12.1
#=GS N1RA31_FUSC4/276-712      AC N1RA31.1
#=GS G9MVN2_HYPVG/263-729      AC G9MVN2.1
#=GS E9E5X4_METAQ/276-754      AC E9E5X4.1
#=GS K2SFJ9_MACPH/285-727      AC K2SFJ9.1
#=GS V5FVA4_BYSSN/272-664      AC V5FVA4.1
#=GS B8M1J7_TALSN/268-651      AC B8M1J7.1
#=GS B6QA45_TALMQ/270-652      AC B6QA45.1
#=GS S7ZMY5_PENO1/268-623      AC S7ZMY5.1
#=GS A2QVK4_ASPNC/269-683      AC A2QVK4.1
#=GS Q4WMY0_ASPFU/269-655      AC Q4WMY0.1
#=GS Q0CKG4_ASPTN/269-654      AC Q0CKG4.1
#=GS F2SKX2_TRIRC/269-695      AC F2SKX2.1
#=GS J3KIG9_COCIM/279-693      AC J3KIG9.2
#=GS L8FZI7_PSED2/262-712      AC L8FZI7.1
#=GS G2Y0Y9_BOTF4/263-746      AC G2Y0Y9.1
#=GS A7EX15_SCLS1/262-736      AC A7EX15.1
#=GS S3DHZ8_GLAL2/261-714      AC S3DHZ8.1
#=GS N1J9F0_BLUG1/263-690      AC N1J9F0.1
#=GS Q7SFZ3_NEUCR/267-697      AC Q7SFZ3.1
#=GS G4NE39_MAGO7/269-754      AC G4NE39.1
#=GS A0A0C4DT95_MAGP6/274-749  AC A0A0C4DT95.1
#=GS J3P9K2_GAET3/282-755      AC J3P9K2.1
C9SIJ2_VERA1/280-735                 LEDED..LYGDVFDTLTPRDIALSRYQQNHEWMEEVWSSPYSLIHITPPDLGLGLKGELAPLTDGIFS....SQGGEAHLENPKKPYVGKLDKGLADEFRKRAQEHIDTTNAEIEKMKADHEAAIAKMKANATILSAEKELRHS....VEERGAEFWRLEGQV...TDSDEGSSAWSQK......HNKKIDDIVAQVEAHLGRQIAVLHGVNRVQAGGYLEPVPEPVKKATPVPVKEATPVAVPNVGAESNDM............SRRPSHAGSQQSGATGDDA......DIDMG.....GTAAGL.......LDEMH.........TGL.SSTSTPL...NFPTP....SGLNSGVATP.ANL.GAPSPAPAAASG..................PGPDVSMANTDA......NKDAAASSGQDQGSGDWVVV...PK..GGVSPDTNANTTPAPAPAPDAAAA..AAAAA.........................AAAATAPTAVAARQGSAVGTPALTE.......GDNDFSSLGDL.DTAGEALAGYDGG..LDGGAGSLGD.GLDLNMEM........EDSAFGDAFHGASNTNT
E3Q6J3_COLGM/263-717                 HDDEE..LEKDLFDHLTPRDISFARYQQNHEWMEEIVSSPYGLSQIVPPDLGLGLKGELASLTDGIFP....AQSADALTEPPQKPYIGRLEPGLADEFRKRVREHLDATKAEMEKMKAEHAKNLASLKASSVFVDAEKDIKNS....VQEHGPEPWRIEGHY...TDSEDNSGPWSQK......HNKKVDEIVAQVEANLGRQIEVLHNVHRIQDGGFQEPAPEPVKEPSPVPPPASSLP..PAAGADTGALG...........SRRPSQAGSTHSGVMVGDS......DIDMG.....GTAAGL.......LDEMH.........TGF.SANSTPL.N.NFPTPQTHMSALNSTAGTP.ANA.NAPSPAPVPPTI...PEETETQASAGASAGAAEDVTMGNTGS.....TKNTPATAPDHGTGSGEWVVV...PK..GGTSPDPGAGAAT.....STGATE..GDEPK..................................AAAKIPSAAGTPVETQ.......TPGGFSSLGDL.DSAGDAMASY.........GASMAD.GLDMNMEM........EDSAFGDAFHGVSSTNT
T0K1F7_COLGC/266-713                 HDDEE..LEKDLFDHLTPRDVSFARYQQNHEWMEEIVSSPYGLAQIAPPDLGLGLKGELASLTDGIFT....AQSANALTEVPQKPYIGRLEPGLADEFRKRVQEHLETTKAEMEKMKAEHAKNLASLKASSVFVDAEKEVKNS....IQERGPEIWRLEGHS...TDADDNSGTWSQK......HNKKVDDIVAQVEANLGRHIEVLHNVHRIQDGGFQEPAPEPVKEPTPAPPPAAS.PQAPAAGAEPSGTA...........SRRPSQAGSQHSGVMVGDS......DIDMG.....GTAAGL.......LDQMH.........TGF.SATSTPV.N.NFPTPQAHLSALNSNAGTP.ANA.NAPSPAPVPPTI...PEESEAQSAPS....GGEDITMGNTEP.....PKDAP.TASDQGTGSGDWVMV...PK..GGASPDPAAAANA.......NATE..SEAPK..................................PTPKAPSAAGTPAGE........TPGGFSSLGDL.DSAGDAMASY.........GASLGD.GLDMNAEM........DDSAFGDAFHGISNTNT
N4W4X5_COLOR/266-721                 HDDEE..LEKDLFDHLTPRDISFARYQQNHEWMEEIVSSPYGLSQITPPDLGLGLKGELSYLTDGIFT....AQSANALTEPPQKPYIGRLDAGLADEFRKRVQEHLESTKAEMEKMKAEHAKNLASLKSSSVFVDGEKELKNS....IEERGPELWRLEGHS...TDSDDSPTSWSQK......HNKKVEDIVAQVEAKVGRQIQVLHSVHRVQDGGFQEPAPEPVKEPTPIPAPTVS.PHVAASGPEPSGPA...........SRRPSQAGSQHSGVMVGDS......DVDMG.....GTAAGL.......LDQMH.........TGF.SATSTPV.N.NFPTPQAHISAINSTAGTP.ANA.NAPSPAPVPPTI...PEEPEAQATTG....GDEDVTMGNTEP.....PNDAPATAPDQGTGSGDWVVV...PK..GGVSPDDAAAAAAAAATTAVPPAD..GEASK..................................PTPKAPSAAATPAGE........TPGGFSSLGDL.DTAGDAMASY.........GGSLGD.GLDMNAEL........DDSAFGDAFHGISNTNT
C7YKL5_FUSV7/261-710                 FDDDEDVSRGDMFDHLTPREIALSRYQQNHEWMEEILSSPYRISQITPADLGLGFKGELASLTEGIFP....TQG.DAFATGPDKPYIGRLDPEKADEFRRRVTEHIESTKAEIERMQAAHAEALAKFKANSIFDSKEKELRNV....VEGTGTEIWRVEGKV...DPLDDDPSPRPVS.......KKTAEDIVSEVENATGKKAVSKPVVSRIQDGGYQAPAPEPTQAAAQL................................SRQASQSGSQNSGVMIGES......DVDMG.....GTAAGL.......LDQMH.........TGI.SATSTPM.N.TFGTPQPNLTA..SGAGTP.SNP.NVPSPAPGQAGATSAP..............GGGDVTMGGTEA.....SKDQTTTAPDQGTGSGEWVVV...PK..DGATPDPNAPANAAAGSGTASANA..NTPNA...........................QGLENKPAAPKTASAGATPAAATPGGSLSFDQNDFSSLGDL.DTAGDALAGFDGP.TLDGSAGELGE.GLDLSMDM........EDSAFGDAFHGVEASGT
I1RC12_GIBZE/261-698                 FDDEEDVSRGDMFDHLTPREISLSRYQQNHEWMEEILSSPYRISQITPADLNLGFKGELASLTDGIFP....AQGVEAFTSGPEKPYIGRLDPDKAEEFRKRVNNHIDSTKSEIEKMQADHTKALAKFKENSLLNTKEKELRNV....TEGTGTEVWRIEGKV...DPNDEDPAPRPTS.......TKTVEEIVSEVENATGKKVEPKPTVSRVQDGGYQPPAPEPAQAGTSQL...............................SRQPSQSGSQNSGIMIGES......DIDMD.....GTVAGL.......LDQMH.........T....STSTPL.N.AFGTPQPQASANQSGVGTP.SNANTAPVP.........................VVGDVTMGGTQE.....LKDSNVTAPDQGTGSGDWVVV...PK..DGPS...NEQADQQPGSGTASVNA..NTPVA...........................PGIDATRSVAKTASAGATPAAGTPGGSVSFDQNDFSSLGDL.DSAGDALAGFDGP.TLDGSAGELGE.GLDLSMDM........DDSAFGDAFHGVDTSGT
N1RA31_FUSC4/276-712                 FDDEEDVSRGDMFDHLTPREISMSRYQQNHEWMEEILSSPYRISQITPADLNLGFKGELAYLTEGIFP....AQGVDASNSVPEKPYIGRLDPEKADEFRKRVYNHIESTKAEIEKMQADHAAALAKFKENSILSTKEKELRNT....VEGTGTEIWRIEGKV...DPHDEDAVPRPVS.......TKTVEQIVSEVEAATGKKVDTKPTVSRVQDGGYQPPAPEPVQADASQL...............................SRQPSQSGSQNSGIMIGES......DIDMG.....GTAAGL.......LDQMH.........TGI.SNTSTPL.N.NFGTPQPQLSAAQSGAGTP.SNTTAVG...........................SGGDVTMGGTQG.....PKDHT.TAPDQGTGSGDWVVV...PK..DGTA...NDQANQGPGSGAASVNA..NTPTT...........................AGIDAAKSVAKTASAGATPAAGTPGGSVSFDQNDFSSLGDL.DTAGDAL.NFDGP.TLDGAAGELGE.GLDLSMDM........DDSAFGDAFHGVEASGT
G9MVN2_HYPVG/263-729                 FDDDEDISRGDMFDHLTPREISMSRYQQNHEWMEEILSSAYRISQITPADLGLGLKGELASLTEGIFT....AQGGEAYSQAPEKAYIGRLDPGQADEFRKRVDKYVSSTQAEIQKMEEEHQKMMTALKEHSLLKIKEKELRNI....IDGHGSAHGK........HQSDDEPVGRHVS.......KHSIEEVVQQVESSSGRKIVSLPLFKRIQDGGYQAPAPEPPAPGSTAEL..............................SRQPSRAGSQASGAMMGET......DMDMG.....DTASGL.......LDQMH.........TGF.SSTSTPV.N.NFPTPQPQISAGQSGTATP.AQAANAASPAPAPAPAPAAP........AAAPPQPSGDIEMGGTDT....AAENEVRTTPDHGTGSGDWVVV...PKDDDKATANDAAQATTQPPVDAATTTA..APAPA...................IGTDAESDEAKPPTPAAAKPPSAAATPAV.TEGGSVSFDQNDFSSLGDL.DTAGDALAGYDAP.ELDGSAGGLGD.GLDLQMDM........EDSAFGDAFHGVDASHT
E9E5X4_METAQ/276-754                 FDDEEDISRGDMFDHLTPREISLHRYQQNHEWMEEILSSAYRIGQIQPSDLNLGLKGELASLTEGIFT....AQGGDVFTQSPEKPYVGRLDPGLADEFRKRVCKHVESTESEIKKLQEEHAELMASFKQNSALKIKEKQIRSI....PDPPVPEIFKAEDRS...DNVEEQRAPALQP......EKTPFDDILKDVEASIGRKIDIHPVIKRVQDGGYQAPAPKPPTPGPTTQM..............................SRQPSQSGSQNSGLMMGDS......DMDMG.....GTAAGL.......LDQMH.........TGF.SSTSTPV.N.NFPTPQAQVSAAQSNAPTP.SNVHNIPSPAPALPTVPEAG....PGSARPSHSHPAGDVDMSGMGA....HSKAQGDSAADQGTDSGDWVVV...PK..GGASPDGNAPSSAVSSAAVTAPTA..AVPIA..............APTVTVGATSGQVAQQKLAPVPTKPISAAATPAV.TDGGSASFDQNDFSSLGDL.DTAGDAMAGYDAP.DLDGSAGGLGE.DLDLQMDM........DDSAFGDAFH.VDSSGT
K2SFJ9_MACPH/285-727                 IEDEENVALGDLLDHLTPRDISTMRYIQHHEWMEEVFSSPYAAGQIMPVDLGLGLMGELAHLTEGLFDAPSASSLPGGQKAPEAPKPYQKLSKEKYQDFEERINSFLKNEEAELEKMKAEHAKKMAELTKSKTYVQAERLLRDAAFS............DSRKAAPATESQSASPFSEG....ADPDVKVNEVVEDVEKSLGVTIAPRKNVNCVEKGGLVDE...........................................PPAPAQTGNEANGTENGATNGESNGGLDDSAMDGDNTAAGL.......LDQY........TSNSL.VSTPGGS.SLQVPPVSQPDSQGQSATATPGGSAQPGHTHEQDQSGSGVQSDNSNGDNGMDLIENMDLDIDMSGMGE.............GANDKAADDWVMVDSNNN..GGN...............GSGEAG..QNKSS..............STTGGGDNDTTIAQGQDGTTTSAPASAAGNTPGM........FDATDFSAF....DTAGDALADY............TGGDDLDLG..L........EGDAFGDAFHGTETRND
V5FVA4_BYSSN/272-664                 LEDEE.VSTGDMLDLLTPREIAKMRYQQHHEWMEEIFASPYATNQITPVDLGLGRKGELESLTAGFFDAPTGPSAPKESKA......AGKMEPGKAEEFADRVAKKVADMTEEIEKLKKRHARRMEKFKRTSLLKDAEYRLRDAAAD.PDATGSELWRLEGRIDTSTE..EGASPVEQTQ...PKPKYKVDDILHEVETSWGKKIVPETKVACVEKGGLLEKIE.........................................HEQPEPEG.................DVSME.....NADSHL.......LDQFGT.PAGSTPGQGATSQAGGTT........................AAGPGNAPNAASAQA...STTGTSQGGIPSVPDLDVDIEMAGTSN.........DQQAPTADGETGDWVMV...ND..DTK.......................KDQAG.......................EGDKSSAQGFTPG.........NTGLETSNFD..DAADFTNI....DSAGDALAAY..........SEQND.GLDLP.DL........ENSAFGDAFHASDNEHS
B8M1J7_TALSN/268-651                 MEDED.ASTGDILDVITPREISKMRYQQHHEWIEEVFASPYTIKQITPVDLGLGRKGELESLTSGFFEAPVTSTHPKDGPNTA..LKEGKMEPEKAEEFADRVAKKVSDMTAEIEKLKRRHERRMQKIGRVSVLKDAEQRLREAGAN.PSETGREVWRLEGRIDTSTEE.EVPTESPLEDISVRVPQYRVDEVVKDLEKAYGKTIVPDPSITCVEKGGLLERIE......A..................................SPAPEDITGA...............DTDM......LMETSI.......LDQFVA.SSTSPPGQGS.QQAAVST.A............................VPATQPT....................GDGDVEMGGATN...ALTQSGT.....AAGETGDWVVV...EN..ENS..............GNVPSVT..ADKP..................................ITN..NAPTGGETSGVETSNFD..DAANFTNL....DSAGDALAAY..........DDQHD.GLDLP.DL........ENSAFGDAFHASDHEMG
B6QA45_TALMQ/270-652                 LEDED.VSTGDLLDMLTPREISKMRYQQHHEWMEEIFASPYTIRQIIPVDLGIGRKGELESLTAGFFEAPVSSTHPKDDKESSVALQGGKLEPEKAEEFADRVAKKVSDMTAEIEKLKRRHARRMAKIGRMSVLRDAELRLREAGAN.PSETGPEIWRLEGRIDTSNEE.EAPIEETVEDISLRMPRYRVDDVVKDLEKAYDRAVLPATSITCVEKGGLLERIE......P..................................TPQPEENAGA...............DTDM......LMENSI.......LDQFVA.SSTSTPGQAT.QQAPVSA.G............................VPAQPATHA...P..............GDGDVEMGGATN...APVQSGT.....AAGETGEWVVV...EN..ENT..................AVL..TDKP..................................TTN..NVPVGRET..VETSNFD..DAANFTNM....DSAGDALAAY..........DDQHD.GLDLP.DL........ENSAFGDAFHASDHEMG
S7ZMY5_PENO1/268-623                 LEDED.VSSGDAMDFLTPREISKMRYVQHHEWMEEIFGSHYAISQITPVSLGLGRKGELESLTTGFFDAPAGGEGQEGQAPD.....ATKLEPAKAEEFADRVAKKVADMTAEIEKLKKQHARRMERFNRSSLFKDAEIRLRAAAAD.PSVTGSEVWRLEGRIIIPNEDGETPQLDYVE....EKAKFKVDDVVRDVEQTWKKQIVPMPKVSCVEKGGLLEKIE......P..................................EQKMEPESFAN..............DMAVD.....QTGSHP.......TDQFGP............STAASNT...........................VPPVPPAPQASK...................DVEMDMGNQAG............GGGTTAESGDWVMV...NK..ENK........................DANT.................................TPG.....ATVGESGIESANFD.....DFTNI....DSAGDALAAY..........TEQND.GLDLP.DM........DNSAFGDAFHASDNEHS
A2QVK4_ASPNC/269-683                 LEDED.VSTGDAMDLLTPREISKMRYQQHHEWMEEIFASPYAINQITPVSLGLGRKGELESLTAGFFDAPVGPASGETKDANTSTQAAEKMEPAKAEEFADRVAKKVADMTAEIEKLKKRHARRMEKFNRTSLLKDAELRLREAATD.PAETGTETWRLEGRVVMPSED.DDSQAPQVE....NPAKYKVDDIVREVEKSWQRQIVPEPKISCVQKGGLLEKIE......P..................................EQKPEPQAEG...............DIDME.....NADSHF.......LDQLGSPSAAGAVPASSTTQEPTAP............TAVPGVPPTTSVPSGGVSVPPQPQPTA..........DATQQGASLDIDMDMGDAQA............TNTAAGETGDWVMV...ND..EKK........................DQPA..............GGDSSLPGISTPGSGIQGLTPG...NGGSAGDSALDGANFD......FTNM....DSAGDALAAY..........TEQNE.GLDLP.DL........ENSAFGDAFHASDNENT
Q4WMY0_ASPFU/269-655                 LEDED.VSTGDLMDLLTPREVSKMRYQQHHEWMEEIFASPYAISQITPVSLGLGRKGELETLTAGFFDAPVGPAGGDSKEGTESAQ.ATKMEPERAKEFADRVAKKVADMTAEIEKLKKRHARRMEKFNRTSLLKDAELRLRDAAAN.PEDTGTEIWRMEGRTEMSTEG.DEAEVVPVE....HKAKYKVDDIVREVEASWRRKIVPEPRVSCVQKGGLLEKIE............................................PEPVSTAADV............DIDMG.....HTDSHL.......LGQFGA.PSQGVAPAAQGQAVPTAT..............................GPAPAQPTV.................SLDAEMDMGDGQP............TNTAVGETGDWVMV...NE..DKK.......................DDNIN..............RPPGDMQAGETPGSGLQGLTPG....PGSAGDTGLDSANFD......FTNM....DSAGDALAAY..........TEQNE.GLDLP.DL........DNSAFGDAFHASDNEHT
Q0CKG4_ASPTN/269-654                 LEDED.VSAGDMMDLLTPREVSKMRYQQHHEWMEEIFASPYAISQITPVSLGLGRKGELESLTAGFFDAPAAPTTGEHKEEPVA...ATKMEPAKAEEFADRVAKKVADMTAEIEKLKKRHARRMEKFNRTSLLKNAEFKLREAAAD.PEELGTEVWRLEGRIVVPTEDEDETEPRPVSD...PKAKFKVDDVVKEVEQAWQKPIVPEPKVSCVQKGGLLEKIE......P..................................ERKEEPTGG................DVDMG.....QVESNL.......LDQFSTLPSTESVPTAQAQAGQPPA..............................APPVAHAST..........TDAAQAGGLDVEMDLGDGKP.............GTAAGETGDWVMV...PE..EKK.......................ADKPT.......................ATSGNGLQGLTPG...NTGSAGDSALDGANFD......FTGM....DSAGDALAAY..........TEQND.GLDLP.DL........ENSAFGDAFHASDNENM
F2SKX2_TRIRC/269-695                 LDDEE.VSTGDILDALTPRDISRMRYKNHHEWMEEVLASPYRMDQILPVDLGLGRKGELESLTKRYFYTP.GALASQRKEGDGPPPATGKMDPGKAEEFANSVAKRLAEMNAEMESMRKKHARKLEKTKKLSALREAELNLRDAVID.PSDTGDEIWRVEGRLRLEQE..EGMSPVDYSD...KSLKKKVDDIVNGLQASWGRTVVPVTDIKCVEKGGLQERVQ.........................................PPPPPPQPAIS..............DANM...................INTLHYSQYDGATDGGA.EAAPGAS........APAQGVPTSAPSQPIVSSVAPPQPVITAPQT...................SEDVVMGGVEP...STQSHATPGQPAAAEGDGDWVMV...NK..DGQASSASPSKDLGSTVNES......TQQPT................STAGAPSTTTAGGTTATVPAAEATVPGTTPGA..TGEFE......DENI....NTAGEALADY..........HGDVG.GLDMG.GI........DDSAFGDAFHATEGNIG
J3KIG9_COCIM/279-693                 LEDEE.VSTGDFLDNITPREISRLRYRHNHEWMEEIFDSPYRINQILPVDLGLGRKGELESLTKGYLEAPAGPSPGAESDAT.....VSKMEPERMEEFTNAVTKRVADVTAEIEALKRRHARRLEKINRLSVLKEGEVALRDAYVD.PSNVGKEFWRIENRLRPIVVTDETMQQVEYNE...PTSRTKVADISAEVQKAWGEPIVPLKEVICVDKGGLEEPVKE........................................SPQPTTEPSAA..............DVDMGNGEDLSKDLELPTAQGESVSEFEAAKQGAQATQEVTGDVSNAA................................................QGNIQAASGPSGDIEMGGVNE.........GQAPASADQLGEDWVVV...NK..DEKTSRDGSPK...............GDQAE..............SIEQPSAPKGASMKEPEGTTPR..NNTGLEAPEVLETSNFE..DAASFSHI....DSAGEALAAY...........EENS.GLDLE.GL........DNSAFGDAFHASEGGHQ
L8FZI7_PSED2/262-712                 .DDEEDTSRGDMFDHMTPREVSQSRYIQNHEWMDEVINSPIPIDHLVPVDLGLGLGGELKKVTNGIFETYNSAKYIEDGKGG.ENEYIGHLDPGKADEFRKRASEKIEADNKEVEKLKRRHARRMAKLAKNGTVLQAEKALRTAVND.PSDVGTEYWRLEGKLPSNDDSDSEEPPPALS......TAAKVDDIVAQLEASLGLHTAAVKELRRLHDGGLQERQPSPEPAPYVPCEIA............................SPQAPSPRSAHSSLLVADH......ELDMG......SAAGL.......LDQFH.........TGF.SAATTPG.NSYTSHHIQGLSTMNSSAPSP.................................AQQQPDVEMGGTAQ.............EGEKSDAGDWVVV...PQ..GGVSPTVVQAQRQAPTPVPAPAPS..APAPAEEQTYVPQSAPASVAATPTAPALAPPAAGAQVGTPAALGVTAASTPRV.....SEAAEPVDFSGLDDL.DTAGEALAGF..........EELEG.GMDL...V........DDSAFGEAFHGVEGGQE
G2Y0Y9_BOTF4/263-746                 .EDEEENSRGDWFDLTTPREISYSRFLANYEWMEEVLSSPYAVNQIVPTDLGLGLRGELSSLTEGIFN....APLKETEEPT..LNYVGRLDPGKADEFRKRAHDTIAQTNKDIEKMKARHAKRLAKFQRGSLISQAEKELRTAVDD.PSDIGPEYWRLEGKI...DEEENEESETPIK......IPSKVDDVLAKVEASLGRHAVAISELRRIQDGGYEEVTARASPP....................................PSQPSRNNSQQSGVLMNDTEIGDVGDVDMT.....NSTAGL.......LDQFH.......NSNPS.SSHATPI.SANYPTP.GHLQH.PSAATTP.AGALHMASPHLSQTMGTPQIT....QQSQSPPQQEQNDVHMQDSTSTAETQQPMTTTAPPTTGADTSDWVVV...PP..GGISPTADPSNNNTNNGTQNSENQNLNQQST...........LSDFGKPSSDNNALEQPNTSTSLPEPQQELQEHQVEQEEQEHHTELNENDF.DLEDL.DTAGDALASYDAGDNME.DGHGLG....DL...V........DDSAFGDAFHGVDHHND
A7EX15_SCLS1/262-736                 .EDEEENSRGDWFDLTTPREISYSRFLTNYDWMEEVLSSPYAIHQIVPTDLGLGVRGELNSLTEGIFN....APLKENEEPTPALNYVGRLDPGKAEEFRKRAHDTIAQTNKDIEKIKAKHAKRLAKFQRGSLISQAEKELRTAVDD.PSDVGPEYWRLEGKI...DEEENEDTETPIK......VPSKVDDVLAKVEASLGRHAVAISELRRIQDGGYEEVAAQASPQ....................................PSRPSRNGSQQSGVLINES...DVADVDMT.....NSTAGL.......LDQFH.......NSNPS.SSHATPM.SANYPTP.GHLQH.PSAATTP.AGALHMASPHLSQTMGTPQAA.....QHQFSPQQEQQDIHMQDSISTAEAHQSMTATAQPT..GDTSDWVVI...PP..GGVSPTADPSNTNTNSNTPNPQSH..DQQSA...........LPDYLKPSS.NNTPEQTTNSTSLPEPQ...VEHSQEQEEQEHHTELNENDF.DLEDL.DTAGDALASYDAGDNMEDDGHGLG....DL...V........DDSAFGEAFHGIDHDHG
S3DHZ8_GLAL2/261-714                 VDDEEDTSRGDLFDHTTPREISESRYKQNHEWMEEVLSSPYAINQLIPADLGLGVRGQLVRLTEGIFD....APLNPDTDVV.KHNYVGKLDPEKAELFRKRVGDEISQTNKEMEKIKAKHAKRMAKFKRGSLITQAEKQLRTAVND.PAATGPEYWRLEGKI...DTEDGDDTPPVTQ......TPSKVSDILAQVEASLGRHAAVVQELICVQKGGYEEPVARPSPRAPVVPSPRV...........................SPPASNNGSQNSGVLVGDA......DIEMG.....GSAAGL.......LDQYH.........TGL.SSNATPA.SGGFPTPQPHLQA.PSSAGTP...NLTGASPRPMGQTS..............MHQMPHNEVNMSNMGQ.........TTEQPLDNGGSGDWVVV...PP..GGVSPSNNIAQAPIHTMQSSHMNA..PTAGT.........................PASAPLTGNPSPHPTGSSNQTPLAD....FHTSPNDFADLGDL.DSAGDALAGY..GEGLGGDSGGLGDLTMDMDGGM........DDSAFGDAFHGVENPGD
N1J9F0_BLUG1/263-690                 IEEEEDTSRGDIFDHITPREISMVRYKQNHEWMEEIVSSPYPMNRIVPADLGLGIRGELSPLTDGIFD....APLDPDKDVV.KHNYVGKLDPEKAEEFRKRVDDQVVQSNNEMEKMKLKHEKRLHKLKKGSIFRTAEKELRSAVFD.STDISPKILQLDGHA...EEAEPEETEALIE......ARRQVSDIIAQVETSVGRKINTVCELIRIQDGGFEEAI.EVIPTLPDPGSPRI...........................SAPIVEKDYNQSQGLSNEG......SLDIN.....NMSVGI.......LD..........YNTGM.PSNLNPTENQHFSTSQNHLQGYPNTATQL.........................TQQNQYSNNSNNTSINQDGSQG............MRTITSQSEAWVSV...PH..GDVILNEN.................................................QKSQLPTQILPQVPIASSTPTKFNGFPEYHPSPNEFGDLGDL.DPSADALAGF.......GEEGSLGDLGMDIDIDVGGDLDALAQVSAFGDAFTTHNNASG
Q7SFZ3_NEUCR/267-697                 FDDEEDVSRGDLFDHLTPREVSIARYQQNHEWMEEILSSPYQIGQIEVSDLGLGRKGALASLTEGIFE....AQSTEAVDHGPKKPYTGHLAPGVADEFRKRVLEKNKADMEEIARMKADHEKALASLRKQSAIMQAEQDLRFA....VQETGSEAWRLEGRL...EDDEDGSSRQGQR......NTRALEEILASVEKIVGKPATVVHDVHRVEDGGYQESAPEPEPSLPSVGQAPPM..........................SRQPSQAGSQASGAIIGDS......DIDMG.....GTAAGL.......LDQMN.......TAGGF.STASTPQ........ALNLSANPSSAATP..SAANVASPQPPATNQ..................GGNDINMEDADA..........EASAKVATSAPDQVPVATNPS..GATTASIPQPPTTAGHSDAVGVPA..QQVPQ..................................PSSKPASVAPTPTG.........EGIDFSSLGDL.DTAGEALAGYDPP.....SVGPGGDDLGDLNMDM........EDSAFGDAFHEVSHSAG
G4NE39_MAGO7/269-754                 YEDEEDTSRGDIFDSLTPRDVSMARYRQNYELMEEILCSPYRMGQIVMPDLGLGLKGELAGLTDGIFE....AQGEGAHKTAPKKAYVGKLDGELADQFRKRVAEQIEATQTEIKALEAQHAKMMAEFESGKLLMRAERDLRGVSKKSDSGSGGDFWRLEGRA...DGIAEDGTISLGR....GVDSKDLDQVVAEVEARVGRKAVAVQDVRRVQDGGYQEPVAPPPRVEPDPVLIEAQQQQQPLLDPMLNHPAASAGPPAASSMSRNPSHPGSQHSGVMVGDS......DVDMG.....NTAAGL.......LDQMN........PSGF.STTSTPV.N.NFPTPQPQLSAAQSNAGTP.ANA.GMPSPHPPPPQP.............QAAPSTSQDVDMGNTET..PASKEPTPPTAPDQGTGSGDWVVV...PK.....NASDAASGSGVMGPSPNGGAG..TPVPA..........PGGAPGGAPAMGNPATVAQKPAATAAAAPASVPAAPTP.....NKPLTPGDFSNLGDLPGSS.......................EFDLNMEM........EDSAFGDAFHGVSESRE
A0A0C4DT95_MAGP6/274-749             FEDDEDTSRGDIFDHVTPRDVSVARYTQNHEWMEEVFSSPYRMSQIELPDLGLGLKGELAPLTQGVFE....APGERAEKEVPKKSYVGRLDKDLADEFRKRVDERIEATKAEMKRMEAEHAKTLAAIEKGRLFARAERELRG.....PSDNASEFWRLEGRL...DGSEDDGRAGGRR........KDPDEVAATVEAAVGRKPVEVQDVRRVQAGGYQEPMVEPPRVDP.........VSQPLLDPLLADPA......AASSMSRHPSHAGSQNSGIMVGDS......DIDMG.....GTAAGL.......LDQMH.........TGFASSTSTPI.N.NFPTPQPHLQAGHSNAGTPQAGA.QVASPHPPPLGQ..........QHQQHPLIASHDVDMGNVPSGEAAGKETTPITAPDQGTGSGDWVVV...PKTTGAETPLGAGTVTAHAPSTAVGSSA..SDDPG..............AGVEPQLEAKPPVAATHMALGASKPSSAMGTP.............DNFSSLGDIVEGGGDALASF.......GETPGVGD.DLDLNMDM........EDSAFGDAFHGVSESRT
J3P9K2_GAET3/282-755                 FEDDEDTSRGDMFDHVTPRDVSVARYTQNHEWMEEVFASPYRMSQIELPDLGLGLKGELASVTQGVFE....AQGEKAEKEVPKKAYVGRLDKDLADEFRKRVDERIEATQAEMKRMEAEHAKTLAEIEKGRLFTRAERELRG.....PSDNSSEFWRLEGRL...DGTEDGGRAGGRR........KDPDEVAATVETTVGRKPVEVQDVLRVQAGGYQEPVVEPPRVEP.........ASQPLLDPLLADPA......TASSMSRHPSHAGSQNSGIMVGDS......DIDMG.....GTAAGL.......LDQMH.........TGFPSSTSTPV.N.NFPTPQPQLQAGHSNAGTPQAGA.QVPSPHPPPPGQ..........QHQQHPVSASHDVDMANSATGEAAGKEATPLTAPDQGTGSGDWVVI...PKTTGAEMPLGAGTVAAHASPAVPGATA..GGDVG..............AGMEPQ..AKPPMAGNMQGLGASKPGSAMGTP.............DNFSSLGDIVEGGGDALASF.......GGTPGVGD.DLDLNMDM........EDSAFGDAFHGVSESRT
#=GC seq_cons                        h-DEE.sScGDhFDpLTPREIShsRYpQNHEWMEEIhuSPYslsQIsPsDLGLGhKGELsSLTcGlFs....ApuscspcsssppsYlG+L-Ps+A-EFRKRVsc+lssspAEIEKhKtcHA+phAKhc+sSllppAE+cLRsu....ss-sGsEhWRLEG+l...s-s--sssshshp.......pp+VDDIVupVEsuhGRplsshppVpRVQcGGapEsssps....s..................................SppPopsGSppSGhhhs-s......DlDMG.....souAGL.......LDQhc.........sGh.SusuTPs.s.thsss..thps..SsssTP.sss.sssuPtss.st...................sssDlcMGssps........ts.sssspussoGDWVVV...Pc..susss..s...s......sss.st..sstss...........................ts..sthsuspsssuuuoPss.p.......s.ssFosLtDl.DoAGDALAuY..........sphu-.GLDLs.-h........-DSAFGDAFHus-ssps
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