# STOCKHOLM 1.0
#=GF ID pAdhesive_17
#=GF AC PF20609.1
#=GF DE Putative adhesive domain (group 17)
#=GF AU Bateman A;0000-0002-6982-4660
#=GF GA 27.0 27.0
#=GF NC 24.7 23.9
#=GF TC 39.2 38.8
#=GF SE Monzon V
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 19856273
#=GF RT Surface protein EF3314 contributes to virulence properties of
#=GF RT Enterococcus faecalis.
#=GF RA Creti R, Fabretti F, Koch S, Huebner J, Garsin DA, Baldassarri
#=GF RA L, Montanaro L, Arciola CR;
#=GF RL Int J Artif Organs. 2009;32:611-620.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC The structure model of this domain folds into 10 beta strands 
#=GF CC arranged in two beta sheets as well as 4-5 elongated alpha
#=GF CC helices.  The beta sheets distantly resemble the Collagen_bind
#=GF CC (Pfam:PF05737)  domain. It is annotated N-terminal to repeating
#=GF CC stalk domains in  bacterial surface proteins. This domain can be
#=GF CC found on a  E. faecalis protein encoded by the EF3314 gene,
#=GF CC which was  proposed to contribute to the interaction of E.
#=GF CC faecalis  with the host and to the bacterial virulence [1].
#=GF SQ 24
Q82YW8.1/70-361     AAVLDIELLSNVTSNNDSGTSTSNRWTAA..NQNQPVNFTV.SGGALADASAVFSGQKQAVLVVPPELRGNVAAAGSAAINTNVT...IDLSKVTFLTAVL........NAANDLTNVITQITSGALGNLTGVDIDLTEVNRQLELVNNIE....NLGAASFTAPETLAADGSYISAPISDGLGLVLAQNVSN....ILQDLNAAVQALEAKGTSi.........psNLVAAAINAALLPVK...-GTVNVAVSGALPLLAVGGSGVNELVDASLLGTTTVTLPTTVSTPQ........-NLSNNLD.ARFVGTVVQT..DLLDVNLLATADGVSNIYF
A0A430AZ49.1/53-353 AAVIDGEILTNLEVSNSSGTSAAAPFPIA..GASHNVDFTI.SGTELAGASLVLAGRKAAVLNIPAPMAGLVKPNGEALIDTSVT...LRLDNMQLVQNVI........TAVEELTELLNEIANGALGNMTGVTLNTDEVLEQLALLDNLS....NIGQAEFTAEQVLSPDGKSIYAVIDDGLGLVVSQNIVD....ILTGLQNAVNSLEAEGSDi.........isIPVAAAINTALLPVK...-ATINTTIDVAVGAAGVGGQLFNEVLDAAVLGDTTVTMPTIVQDPTfedlenagIDTSQPYE.AVFPGTVVKD..DLVDLSIFADADGRTSIWF
A0A6L6HBP0.1/50-341 AAVLDAEILSNISSSNDSGTTAGSRWTAD..GSAQNVNFSI.SGGELVGASAIASGTKQAVLAIPNELRGNVATNGAATVNTNVT...LTVGDLTFLTGTL........DAVNDLTNLLTSILDGTLGSLTGVTLNLTEVNQKIDAINNLE....NLGSATFSANTVLASDGSYIQANLDDGLGLVLAQNVSG....LLQDLKAAVDALQATGSGi.........asNVVATAINAALLPVK...-GTVDTAINLAIPLVNVGGSGVNQLIDATVLGSTSVSIPTTITSPT........-NLSQNLD.ARFVGTVVKA..DAIDVSLISTANGVSNVYY
F3YCK8.1/51-346     AAVLDMEILSDIKASNTSGNTENARWTSD..DVNKAVNFQI.TGKELVDASVITSGKKQAVLTIPTEMNGKVTPNGQATIVTNLT...IKLSEIQVLNDAI........NAMEQISNIISKIASGDYGELSNVTINFDEVNQKLDAFNNLK....NLGTATFNENMVEASDGTYISANIDDGLGLVVSQNITN....ALNDYDAAVQALTAKGTGi.........vgGATATAINAALTPVK...-GTVNLAVKAVLPLISAGGSAINQLADASVLGGTTVTLPTLVSPPSd.....taFELSKNVD.AKFVGSVVKS..DQIDASLISTGNGTTFIYY
R3WM93.1/54-354     AAVISGEVLTNLSLSNSSGTSTTSPFITD..GSTRNVDFTI.SGNELVGASAVLNGRQAAVLTIPSDLVGLVNPAGNASIDTSIT...LRLNEIGLLQEVI........TTTDNLVDFLATTLEDVVGNVTGVTVNVAAVNEQLALLKNLS....NFGQAQFSAPQVLTTDGKHIYAVMDDGLGQVVAQDVTT....ILTDLQKAVTELKATGSNi.........itNGLANTVNLALAPVK...-LTVNTAIEAAKAATGVGGLLITQIADAAVLGDTQVTLPTTIKDPDlspsnknnTRALSAVE.EQFSGTVVKD..SLINLSIFSEADGRTSIWY
A0A242K991.1/53-342 AAVLDVEILSNMQTSNNSNTSSTVRWQPT..VTNQPVNFTI.SGAGLANVSANLVGKKYGVLVIPSQLSGKVTPNGNAQVDTNVT...VDLSKVALLKPTF........DALDGLITLIDNIQKGAL-SLVGVSFDLTEVNKQLALLDSLE....TLGHTTYSATTV--GDARSIYLNMDEGLGTILAGNLRQ....ILVNLNTAVQNLKVTVTTpi........vgDAVAAVINPVLNTVK...-PALNTAITTLLPALGVGGAAVQQLADASVLGQTTITLPTFVSGPG........-SITSNLD.ARFVGTVIKS..SVIDIDLLNTANATSYIYF
R3TY21.1/44-334     -AILDVEILSNLKVTNTSGTTTSNRWAQQ..ASNQPVTFEI.TGNSLVSTNV-LTGEKTAVLLIPEELVGRVLPNGNAALQTNVT...VDLSKVALLANVL........TLVGDLTNLIARISSGALGSLSGVTINLAEVNTQLALLKSFE....NFGQASFNQPQVLSSDKRLITTSVDKGLGPVLGSNLAV....ILTNLLNAVKNLKATGSDi.........asNLVAVAINSAIDLVR...-TPLVAALNTVIPTLTGTGPIIQQLADASTLGNTDVKMPTLVSGPT........TTYTTNLD.TKFIGTVVKS..SAITVSLISGSSSQTFIYF
A0A069CUH0.1/64-357 AAVLDINLLSNMAVNNDSGTTTTNRLQA-..GEQRNVNFTI.SGTTPIGVSA-LNGKRYAAVTVPSELRGAVTANGNTVTTTNMT...IDFNKISSLNELI........SVSDSLATKITEILDGSLGDISGVNFDTTDLYKNLNLLKNVQ....SIGGASFNSATTVNSDGSIVSAELDDGLGSILSQNLIT....ILNSLETAINNLHATPKNsln......piqVTLAEAINAALVVPK...GLVNTAITGVLTPLVNGTGDITNELVDAAVLGDTSIVVPTQIKTPS........-DLSGSLD.ARFVGAAVQT..DLLSIDILNTSDSDTFVYF
Q9CFY6.1/52-333     AAALNIDLLQNITSSNNSGTSTTNRWTSN..SGSHNVDFTI.SGGALANISV-LPGTRYATLVVPPELRGYVAATGNTSVSTNIT...IDFNKVALITAIV........NAGDTLISDIAP----LLSSNPLVTLNLAQVTQQLNLLRGIQ....DIGGGTFTSTTTLSNENALLSAPLDDGVGHILSLNVKT....ILQNLETAVNNLNAT---............GTGAIAVNAALTPLK...LVLNGAIDDVLLPLTNGTGNILDLLLNVSALGDTTITIPTKITAPT........-TIQSNID.ANFVGSAVQT..TLLDVNILSGANGISYVYL
A0A179EUS7.1/56-355 ADLISGQLFSNLTSSNTSGTTSSAPYPLE..NTSRAVDFII.SADSGIDLSV-LPGNRLAVLAIPEEMQGLVTPNGDGTFSTEIL...LPTNALDPLLTVV.......nGAVTTLVNGINA----ALALNPLATVDLSQVYTQLDLLNNLS....NLTAADVALQLEAQGD-EYIYAELEGVLEVIIRESLTD....ILTDLNNAVQSIQAVPTSgsg......iagTIAASAVNGTLNATL...KPAFTLTYNTALALVNVGSALIGNLVDGSVLGETTVTIPTLIQDPTyqdlltagVDISNPYE.AGFLATMIKS..SLLAIDIASNYDGYTPVFY
A0A1H9Q153.1/47-338 AAALDYEILSNMKSSNNSGTTIEDSWSAD..GSSQKVDFNL.SGDPLNGTPIITGKTKSAVLAIPPELTNQVLPDEPAQIKTNAS...LQVVDVALLEETI........LASDQLIQLISSIAAGSLGSLTYIQFDAIEIQQKIDQLNHDL....LFNQLIFSTMPILSADGSFIQVDLHESLNSVMRERLDA....ILLDIAECTERLHAKGTNm.........lgNIVAKNINTVLDPAK...-TQLITAITAARTLLQTNTGGAEEIARFSVLGATEVTIPTIVTAPQ........-HLAQNLA.ANFVGTVIQV..DVIDIEAIRQGQGISTIYY
A0A069CU07.1/42-332 AALMGIEVLGNIQSSNDSGTSTTNRQPL-..GSQKAVNFKI.TGDQLVNASV-LTGPRNATLTIPAQLSSAVSLNGSATVKTKLN...IDYRAVSGLKDVI........TTVTTLLTKVDEIINGSLGALTNVTLSDAELVAALKKFQTAQ....VLDEKTFSKTGQLSTDGQLITVPLDDELGKILTADLTT....DLQSLKTAVNNLHASANNv.........lgSTLATLINTTLAPLK...AAAVAAIDLVLSPLVAGTSPLTSDLINLAVLGHTEVTIPTNIKSPS........-NLAHDLD.GRFVGSVVRT..NTLDIGLLNSATSESYVYL
A0A2V3WH67.1/64-365 -SLTEVQLLTDITVGADLIDQ--------..TDYYDLALNM.TGTGLADAELLTPE-RVAVFYIP-DLAGKMQANDPANVRVEIL..pITMDDLPVINGLIgnltgattDLLAGLTSGIDDAINNTPLAGLVKVEGLDELNTAIDNLNNIDqalaDLLVYEDQVDVVVNPDGSVV-VNFSDGIGNHLETAVKDvvtaTITDLLDAIDGLEITLLGgdpt...gllsgLLNNLIINPIVNPLK...SAVVNTANPILNELADGSIDLANDLAGVQVIGQTSVTANVTVEKPA........-GVTGEVP.--IYAAGVST..SVIDVQLLSSLADETSIVF
F8I179.1/62-343     AAVVHGELFSDINTSNNSGTSAQSGLDP-..SQDNNVNFTI.SGGSAVDVSLLGDNKKYAVLGIPTELQGKVVANGPAQVTTNIT...VPLDKFALLKTNL........DLIHTLVNEVNR----LQGLYPGVHADLTGVNNALDAVET--....ALNSTTGSYNTSIQDNGTYLSADIGTGSSEIIANNLVT....ALSQLETAVNNTTFT--G............GLSSGLANTALAVPK...-KLAIDALEVSKTGLKSGGDLFNQIANISLFGSTTVVMPVTIKTAD........NLDNGKVNtEKFVGTMANP..NFITVDLFTNSSGSSNVFI
Q5WJD3.1/64-353     ASLTEFQLLTDVAVNAQLGDADE------..NGLYDLGLSL.TGRGLADAELFGPE-RTVIFYSP-DLADKWTVEGPAQVRVEIL..pVTMDALPTLGNLIgditqqlnSVVNDLVNTVDGIVNNPITAPLIRVSGLTELQDALSALNNIDgalaDLLAYNDEVEAVVQPDGSIL-VNFSDGLGNHLESAVQDvvvqLLNDVVDAIGNVSID---............-ILGGGISVPLEPLQ...-ALVQPLLGLIDNISSGAVDLSNDLAGVQLLGSTEVTLNAKVDG-T........-DVSGEVP.--IYGAGVHD..STIDLQLLNSIGDYDTVIF
K6DA99.1/37-332     -TLVEVKVLTDVNVNATLNPGT-------..GDHYELGLNMsSGDGLLDVKLVGAD-GVAIFYAP-DLAGKLSVEEKANVRVELL..pVTMNDLPTLNNLVgqltselnGLVNKLVGGIESILNNPLTGWLLNVQGLTKLTTSLTALNNLNksleDLTAYNGQADVQVLDNGLLI-VDFGEGLGNHLNTVVNDvvieLLENVADAIEGVKVGGVA...........gYLLSPVVNPTIGLLK...GLVTTMINPLITNLTNGVIDLTNDLVKLHVIGNTTVSLNVLLDKPA........----GVVGeTKIYGAVATD..ALIDITLLSKLTNWDSIFI
A0A1H9TQL5.1/50-321 AGLADVNILSNTSLTSKPSVDMV---PNE..NGNYDVDLTF.TGEALASVGL--ADSKVVVFSLPPELKGKVVGNATVDINVKFL..pFTPADLPAVKLLL........GTLNTALNALKT-------VAAVAGVNLTPIVDAITQLQSLQ....TFGDYNTTVTGTVSPDGSSISVDYTSGLGSYVKTTYAA....LFNTVQAAITTVRNTVPG............GLIGAPVRAALDTLQ...-LALNPILTVVTAIVGGTSNVLDDFFSASLLGQNTYRARFEVQPPG........-----TAQ.ATIHAATVNT..PLINANLLSLINSEGAN--
A0A430AVY3.1/37-307 -SLIGIELFTNQVSTNNSNSTYQAPLIFDpiSNKKNVDFKV.TGQALTDVNI-LNGQKQVILVIPEELIGEVSPNGQAKIEVDV-...LLSEKAPVIGGLL........GTISKLLKDILG----ILGLVLPISKQISALLDRLFNLGRLS....--------YTADILNHGSYLLIDYETGLVSAIIHNLQG....VVVELQNILKGLSGN---............----ILIGALIGPLT...----TAINNLSNALANPSAELLDSLANASILSNTEVVFPTTINKPQh.....diYGDINGISkKDFHMHIVQT..EVIELDVFKDSNSLSSIYL
A0A5R8QDZ6.1/34-322 -SATDIILWSDTTLSSDKPVISE------..TGTHDINFTL.SAFTKDELRLLVQS-KTASFKIPEELVGKIEANGDAQIEIT--...YELAKALFEELGInnlvstidNGVDKLAAFLAE------SELFGYNVNFDDIYAALDLKTIWD....NISVLSLNAPVTVSEDGAYLSVTFEDNAFDKIAEVLRD....IINNIGTALDTFEIT-NP............GVMGGIISSIAMSMWdvvVDAYDLLAAPILHSLVDGADLIASIGDFRTKFTTKVILPTTLTAEYdf....fkTYAPHGLT.VEVDGTFTTP..ALIPIELWTDRHDTTTITF
A0A2X4WVV9.1/1-247  -----------------------------..----------.-----------------------------MTAAGPADVRVEIL..pITMDDLGTLNETLngvttvltGTVTEVLSVVDQLQSSLIPNELLTINGISELESAVDALNNIDdaltDLLAYEDTIETTIAEDGS-ITVDFSDGLGNHLETAINEvvvtLLEDVVTALNGVELAILPgaeeipgvgliiGGLNDLVNGVLGTVT...-GTVDEVVGLIDDITDGTIDLTNDLVGLQVIGQTSVNLNVNVDKPI........-GIIGDVE.--VTGAAVNT..GVIDLELLGSLTDSTTVTF
Q38Y93.1/50-308     AGLADVSILQNASLTSTTGTQMTPN---A..EGNFDLSLNY.TGQGVATVGV--ADKKVLVYALPASLQGKVVGGSTVDIQADLL..pITPGDIPGVKPLF........DALGLAITALDK------------ALKIPAVVAAFDDLKQVQ....SLGSYQETVTANVSPDGKTISVDFTQGFGRYVHQAYAA....LFHSLRDAIAAVHSD---............---NILIETLVKALQ...-KASAELFEVIDAIAGGTSTILDSALSGNLLGSASGTLHTTVSDPG........------VPtATVKAAAINN..ALISADILTAIEQEG----
A0A179EVK5.1/32-285 --ALSLELFGTTTLSNNSQTTVEEPF-LH..VENTPVTFVL.TGEDGVGIGAITTGEKYGILEIPTEMVGYVQVNGPATVQTTVT...VPLSQSP-LQVLM........PTISSVISLIVN-------SPLVSAANKTAVNQALTELTS-E....NFGSQNLSLAITPRTSTQF-EVAISQGLLPILATTLKN....RVQNLLTVVT--------............--AIPLIGTVLGVLL...TPFTTALNQLINNLNSPTSADSRALVAGSILGNTQASLPFLISSPA........--ITSDYV.ANFSGMFIQTdeTLIQL--------------
A0A5R8QIW4.1/67-240 -----------------------------..----------.-----------FTGTKTISIPIPAELLPAAALIGDAKLEITYElaqVLLQNL-GINNLI........RTVDNAASKIMEFLNES--ELLGFNVNFDEVYAALDVQNFWE....SMPTALINSPITLSTDGVNVNVTFEETAFANIMVLVEA....ALANISNAIHAVQLTGQ-............GVVGTFIARTVMDLW...-VVVEDVYDLFAQTVSDI----------------------------........--------.----------..-------------------
A0A2W2DRB6.1/2-64   -----------------------------..----------.-------------------------------------------...-------------........------------------------------------------....--------------------------------------....------------------............---------------...-------------LTTGTGDTVNQLVDLSILGSTTVTIPTQVTPDG........--TQDSVS.--VKGAIARS..ELINVDLFANSAGTTP---
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