!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A0A1D8PRX4_CANAL (A0A1D8PRX4)

Summary

This is the summary of UniProt entry A0A1D8PRX4_CANAL (A0A1D8PRX4).

Description: Fth2p {ECO:0000313|EMBL:AOW30888.1}
Source organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (NCBI taxonomy ID 237561)
Length: 511 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam FTR1 9 184
transmembrane n/a 12 34
disorder n/a 42 70
low_complexity n/a 50 69
transmembrane n/a 90 116
low_complexity n/a 94 114
transmembrane n/a 128 149
low_complexity n/a 131 151
disorder n/a 175 180
disorder n/a 202 210
low_complexity n/a 211 248
disorder n/a 214 220
disorder n/a 222 224
disorder n/a 229 235
disorder n/a 238 240
disorder n/a 242 257
Pfam FTR1 270 469
disorder n/a 279 280
transmembrane n/a 295 316
transmembrane n/a 328 347
transmembrane n/a 359 379
transmembrane n/a 438 457
low_complexity n/a 494 509
disorder n/a 496 511

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A1D8PRX4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIKFEDYFSI QIFFIILRET LETAIIISVL LSFINQRSHK QEEESTLSTN
50
51
NNNNNDNNNN NENENENENA VHPISISQSR KADMNRKLKF QVWIGAILGL
100
101
IICFIIGIIF VLIFYFVGQD YWSYTERVWE GLFSILSSII ITIMGIGLLR
150
151
INKVMKLKWW IKLGDAYNYN GQQDEREDDE EISALTDNDI LFDGNNNGEE
200
201
EDIMNYGGTR SSSESNEIIT HNNNNDSNFS FSSSSSSNSN SNFNSNSNPG
250
251
ILNNDNEESI PLTASSNFFT PFKNKHQSTA KNSKQLHRQS FSKKYFLAIL
300
301
PLVTTLREGL EAVVFIGGSA MSSSPHSIPL SVICGISMGS IIGYFLYQGG
350
351
NKLSLQYFLI FSTCFLYIVS AGLMSRGIWF LELEQYVRQC NGLDVSETGS
400
401
GPGSYDIVKS VWHVNCCNGL TDGWWMVFNA IFGWTNSATY GSVFSYMIYW
450
451
TMVIIWLKIK LYEERHGILP LVPLKWQLKR IQKRIRLYEL RKNHEQEHQG
500
501
QQQEEGQQEA S                                          
511
 

Show the unformatted sequence.

Checksums:
CRC64:70C484D0FFF78E39
MD5:a89cba7c08fe8267bb88b6ef171898dd

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;