!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HXNS_EMENI (A0A1U8QNG8)

Summary

This is the summary of UniProt entry HXNS_EMENI (A0A1U8QNG8).

Description: Nicotinate hydroxylase hnxS {ECO:0000303|PubMed:29212709}
Source organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (NCBI taxonomy ID 227321)
Length: 1350 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 41 60
Pfam Fer2_2 64 146
disorder n/a 76 77
disorder n/a 119 120
disorder n/a 159 187
low_complexity n/a 160 173
low_complexity n/a 179 199
disorder n/a 192 193
disorder n/a 210 220
Pfam FAD_binding_5 258 443
Pfam CO_deh_flav_C 452 558
disorder n/a 577 597
Pfam Ald_Xan_dh_C 608 715
disorder n/a 615 616
disorder n/a 654 655
disorder n/a 663 672
disorder n/a 678 679
Pfam MoCoBD_1 725 972
disorder n/a 740 744
disorder n/a 747 750
disorder n/a 786 791
disorder n/a 799 803
low_complexity n/a 832 851
disorder n/a 853 858
Pfam MoCoBD_2 997 1270
disorder n/a 1093 1095
disorder n/a 1097 1105
disorder n/a 1309 1310

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0A1U8QNG8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDALLPRSSP QLKFYLNGTP ISLTSPHPRW TLLDFIRSQD GLKGTKLGCG
50
51
EGGCGALSGK HVITIEGLGT VDHPHPLQER IAQLHGSQCG FCTPGIVMSL
100
101
YAMIRNAYDP VTGKFQLSAD DIESKGHLDG NLCRCTGYKP ILNAARTFIE
150
151
DDLGSVPSIV ESELVGTEEE TESDMGAHSG SGDTGSRSSG SCGRPGGCCK
200
201
DSPGISSCSS RETDMTTPSL PDSPVLKQYD FIPYTPTTEL IYPPGLAKFV
250
251
PELLCYGDAE QAWVKPRSVQ EALEILSQCP SATLVTGASE VQVDVRFKDF
300
301
RPSVSVFVGD ITEMTGISWS EDMKTLYIGG SASLSDIEAE CLRCIPLLKA
350
351
VNLGSESVLS AIARTLRYFA GRQIRNAACL AGNIATASPI SDMNPLLLAV
400
401
GATVHARTSA EETTIPMSEM FKGYRKTALP SGSLITKIAV PMPSKDQIEI
450
451
VNAYKQAKRK DDDIAIVTAA FRVRIAPGPD YTVQEASLAF GGMAPTTVLA
500
501
HKTASALEGK RWGDEAVLDI VLTSLGEEFN LPYSVPGGMA TYRRTLTLSL
550
551
FVRFWNYVNQ KLGLEYDSDL IEEIHRGIST GTRDDDNPHA QRVVGQQIPH
600
601
LSGLKHATGE AEYVDDMPPL HRELHGALVL SERAHAKILS VNWTPALERG
650
651
AVGYVDHTSL PEEKNHWGPV VHDEPVFAKG EVHAHGQPIG LVYADDAMTA
700
701
QIAAKAVIVT YEDLPAILTI DEAIEARSFF NYGKELRRGA PPEEIRKELD
750
751
DCEYTLSGTT KIGGQEHFYL ETNAAIAVPH TEDGSMDVWS STQNTMETQD
800
801
FLSQVTNVPR HKINARVRRM GGAFGGKESR SVPIACIVAV AAKKARRPVR
850
851
IMLNRDEDMM TSGQRHPVQC RWKVGFNREG KLLVLDADTY NNAGYSVDMS
900
901
AAVMDRCLTH IENCYYIPNV WLRGWVCKTN THSNTAFRGF GAPQAMYITE
950
951
SIISAVAEKV GIDVDEIRRR NLYQVGQRTP FNQVLDEDWH VPLLLEQVRE
1000
1001
EADYDARKKE IERFNSEHRW RKRGIALIPT KFGISFATAL HLNQASAAVR
1050
1051
VYTDGSVLLN HGGTEMGQGL YTKMVQVAAQ ELRVPVDQVY TQDTSSYQTA
1100
1101
NASPTAASSG SDLNGMAIKH ACDQINERLR PYREKYGEDA DLGTIAKAAY
1150
1151
RDRVNLSAAG YYKMPTIGYE WGNYSENVKP MYFYFTQRQG VACTEVELDL
1200
1201
LTGTHTVLRA DLKMDIGRSI NPAIDYGQIE GAFVQGQGLF TMEESLWTRS
1250
1251
GQLATRGPGT YKIPGFADIP QVFNSSKGIG EPPLFMGSSV LFALRDALSH
1300
1301
ARRERGVSEP LVLDSPATVE RLRLAVGDDL VHRAQVQRKD GEQGFFVAVA
1350
1351
                                                      
1350
 

Show the unformatted sequence.

Checksums:
CRC64:8382A423475914B2
MD5:53c3f96589055205ce030039f58be7b0

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;