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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_METTP (A0B977)

Summary

This is the summary of UniProt entry MUTL_METTP (A0B977).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanosaeta thermophila) (NCBI taxonomy ID 349307)
Length: 557 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HATPase_c_3 21 134
Pfam DNA_mis_repair 210 328
low_complexity n/a 322 342
disorder n/a 343 345
Pfam MutL_C 370 514

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0B977. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPRIHILDEE TVSRIAAGEV IERPASVVKE LIENSIDAGA SRIIIEVENG
50
51
GISLIKLVDD GCGIEREDLP LAFQRHATSK ISTADDLFRL KTLGFRGEAL
100
101
SAIASVSKCV EVHTRTRYSP VGTYLRLENG RVAEIKDDGC PYGTSIEVRG
150
151
LFETIPARLK HLSSPSQELA RIAEIVTQMA IIHHRISFEL SSGRRTLFRS
200
201
NASETWDDAL IRAFGLRTAK GMISIIAEGD GFDLHGMISS HDSSHHGSEL
250
251
ILVYVNSRPV YSKVVVQALR EAYRGFLQSG RSPLAVISIE IEPSLVDVNV
300
301
HPAKREVRFL REDEVYDAVR DAALSALRSS AIPSPPPPAR IAEPQLWSAK
350
351
PQIQRTLPLE VQAEQRISEP LIRIVGQALD LYIIVEDDDG IMLVDQHAAA
400
401
ERIRYEHLLE KCKSGSISQE LIQPVTVELS PGEVALLDSF SGELGEIGFE
450
451
IDPFGGRAYS VRSVPAAAGL ESPESIRDVL REILNLGRVC RASFRDEALK
500
501
HLACRGSIKS GERLSESAML RLLTDLFACD NPRTCPHGRP VVVRISSESL
550
551
EKMFGRR                                               
557
 

Show the unformatted sequence.

Checksums:
CRC64:9002F317AFD48B50
MD5:1cf564af4b5f1f711d21543d7f7185cf

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;