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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUTL_AERHH (A0KGR9)

Summary

This is the summary of UniProt entry MUTL_AERHH (A0KGR9).

Description: DNA mismatch repair protein MutL {ECO:0000255|HAMAP-Rule:MF_00149}
Source organism: Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) (NCBI taxonomy ID 380703)
Length: 622 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam HATPase_c_3 21 142
low_complexity n/a 115 126
disorder n/a 119 122
disorder n/a 125 126
disorder n/a 132 135
Pfam DNA_mis_repair 212 330
disorder n/a 340 341
disorder n/a 375 404
low_complexity n/a 420 440
disorder n/a 425 426
Pfam MutL_C 437 580
low_complexity n/a 449 462
low_complexity n/a 456 471

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A0KGR9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPIRILPPIL ANQIAAGEVV ERPSSVVKEL VENSLDAGAD RVEIDIDKGG
50
51
AKLIRIRDNG SGVAKDELVL ALSRHATSKV ATLDDLEGIN SLGFRGEALA
100
101
SISSVSRLTF TSRTAEQSEA WQAQAEGREM SVTIKPAAHP VGTTVEVVDL
150
151
FFNTPARRKF MRSEKTEFAH IDELVRRIAL SRFDVTLILR HNGKVVRQYK
200
201
AANTVAEQER RLAAVCGSPF MHYALAVESE HSDVRLWGWL ATPEGARPQN
250
251
DLQYTYVNGR MMRDKLINHA IRQAYDELLP ADRFAAYVLY IELDPRQVDV
300
301
NVHPAKHEVR FHQARLIHDF IFQALFTALR QQGAASDEPL AETLVELPVS
350
351
APIEYPGQAP RAEWYGAEHN YRAPAREVRE GSSTGRAGNY QPPEPPSREA
400
401
MRGMGSLLTT LPAVQGTPLA EAETAPVAAA VPAKAGAWRA LTLVEQAYLL
450
451
LERDNRLALL SLVRAERLLL RHWLLETWGQ GLAAQPLLLP VSFKLPKNLV
500
501
ALVEQQDRLL KRMGLELKSG GRDTMILTRV PALLRQTDLV RLLPELLQLI
550
551
ESGSDSDAGQ QAEVLCQWLV EQGISREKVY DFATANRLLT ELVADFSDQL
600
601
ANVRMVRPLA LASVLAEFAD GH                              
622
 

Show the unformatted sequence.

Checksums:
CRC64:629FD61F4C6E375F
MD5:0495b4432898c051e736a9fe2ff9e8f5

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;